Publications by authors named "Shanmugapriya Dilliyappan"
Article Synopsis
- - Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting 8-13% of women, characterized by multiple cysts in the ovaries and symptoms like insulin resistance, excessive hair growth, and irregular menstrual cycles, influenced by genetics, lifestyle, and environment.
- - The condition is linked to various serious health risks, including type 2 diabetes, heart disease, and infertility, with its complexities often passed down through generations due to maternal inheritance.
- - Advances in diagnosis and treatment, from Rotterdam criteria to modern technologies, emphasize the importance of lifestyle changes and medical interventions in managing PCOS and its diverse impacts on women's health from puberty to menopause.
Article Synopsis
- Advances in biomedical engineering, particularly microfluidic chip technology, have significantly improved disease diagnosis and patient outcomes.
- This review covers the application of microfluidics in diagnosing various serious conditions, including autoimmune disorders and infectious diseases like COVID-19.
- Microfluidic platforms enable compact, efficient diagnostic solutions that integrate several laboratory functions, allowing for precise and early disease detection.
Microfluidics is a science and technology that deals with the concept of "less sample-to-more precision" enabling portable device development via fabrication for in vitro analysis. On evolution, microfluidic system lead to the development of Organ-on-chip where recapitulation of organ's functionality and pathophysiological response can be performed under controlled environment. Further microfluidic-based "Lab-on-chip" device, a versatile innovation credited for its number of parameters that has capability to leverage next-generation companion of medicines.
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