Publications by authors named "Shanmei Zhong"
Identifying the prevalence and risk factors of secondary human immunodeficiency virus (HIV) transmission from people living with HIV (PLWH) to other people is crucial for ending the HIV epidemic. However, the data among antiretroviral therapy (ART) patients is limited. This study aims to assess the prevalence and risk factors of secondary HIV transmission among PLWH receiving ART by longitudinal molecular networks in China.
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- The study focuses on the spread and evolutionary history of HIV-1 CRF55_01B in Guangxi, China, due to increasing concerns about this strain.
- Through molecular network and phylogenetic analyses, researchers examined transmission patterns between Guangxi and Guangdong Province, and how different populations in Guangxi were affected.
- Findings indicated that CRF55_01B was first introduced to Guangxi from Shenzhen in 2007, with Nanning identified as a central hub for transmission, and highlighted the significant roles of heterosexual contact and MSM in the ongoing spread of the virus.
Background: HIV-1 CRF65_cpx strain carries drug-resistant mutations, which raises concerns about its potential for causing virologic failure. The CRF65_cpx ranks as the fourth most prevalent on Hainan Island, China. However, the origin and molecular epidemiology of CRF65_cpx strains in this area remain unclear.
View Article and Find Full Text PDFBackground: The burden of depression symptoms has increased among individuals infected with SARS-CoV-2 during COVID-19 pandemic. However, the prevalence and associated factors of depressive symptoms among individuals infected with SARS-CoV-2 remain uncertain after optimizing the COVID-19 response in China.
Methods: An online cross-sectional survey was conducted among the public from January 6 to 30, 2023, using a convenience sampling method.
Prevalence of drug resistance (DR) challenges the epidemic control of human immunodeficiency virus (HIV)-1. However, little is known about DR among patients with antiretroviral therapy (ART) failure in Guangxi province, China. This cross-sectional study was aimed to investigate the prevalence of DR and the characteristics of DR sequences in the genetic transmission network among HIV-1 patients with ART failure in Guangxi.
View Article and Find Full Text PDFObjective: This study investigated prevalence trends and identified the associated factors of HIV, syphilis and hepatitis C virus (HCV) among pregnant women in the Guangxi Zhuang Autonomous Region (Guangxi), Southwest China.
Methods: Serial cross-sectional surveys were performed annually among pregnant women in Guangxi from 2009 to 2018. Blood specimens were collected to test the prevalence of HIV, syphilis and HCV.
Introduction: Pretreatment drug resistance (PDR) is becoming an obstacle to the success of ART. This study investigated the prevalence of PDR and the transmission clusters (TCs) of drug resistance mutations (DRMs) in two cities where drug abuse used to be high to describe the local HIV-1 transmission dynamics.
Methods: Plasma samples were obtained from 1,027 ART-naïve patients in Guangxi.