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Publications by authors named "Shanling Shen"

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Synopsis of recent research by authors named "Shanling Shen"

  • - Shanling Shen's research focuses on enhancing anti-tumor immunity and the design of therapeutic agents, particularly through the engineering of cytokines and the development of small-molecule inhibitors targeting key biological pathways.
  • - One significant study explores the combination of engineered IL-21 cytokine muteins with anti-PD-1 antibodies to improve CD8+ T cell function, addressing the limitations of anti-PD-1 treatments in cancer therapy.
  • - Other research contributions include the development of SphK inhibitors and guanine-derived compounds that disrupt the eIF4E mRNA cap interaction, which are integral to mRNA translation and cancer progression.

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