Visible Light-Responsive Composition-Dependent Morphology and Cargo Release in Mixed Micelles of Dendron Amphiphiles.

2,2-Bis-(methylol)propionic acid-based second-generation polyester dendron amphiphile (T-D) containing visible light-responsive donor-acceptor Stenhouse adduct (DASA) as hydrophobic tails is synthesized. Micelles of T-D amphiphile and its mixed micelles of varying compositions with nonresponsive dendron amphiphile containing lauryl groups are prepared in aqueous solution. In transmission electron microscopy and atomic force microscopy analyses, T-D amphiphiles show rice grain-like ellipsoidal micelles as the predominant morphology.

Permeable polymersomes from temperature and pH dual stimuli-responsive PVCL-b-PLL block copolymers for enhanced cell internalization and lysosome targeting.

A series of dual stimuli-responsive block copolymers comprising temperature-responsive poly(N-vinylcaprolactam) (PVCL) and biodegradable pH-responsive poly(l-lysine) (PLL) of varying chain length were synthesized by a combination of free radical polymerization and ring opening polymerization. The block copolymers formed micelles and vesicles (polymersomes) in response to temperature and pH, respectively, in aqueous solution. The nanoassemblies were characterized by transmission electron microscopy and dynamic light scattering techniques.