Publications by authors named "Shanjun Shi"
Background: Gout is a chronic inflammatory diseases caused by monosodium urate crystal deposition. However, the role of interleukin (IL)-36 in gout has not dbeen elucidated.
Methods: We enrolled 75 subjects, including 20 healthy controls (HC), 30 patients with acute gout attack and 25 patients in remission.
Article Synopsis
- Ankylosing spondylitis (AS) is a chronic autoimmune condition, and the study aimed to analyze serum levels of IL-36γ in AS patients to investigate its association with the disease.
- The research included 131 participants: 45 with active AS, 46 with inactive AS, and 40 healthy controls, revealing significantly higher IL-36γ levels in both active and inactive AS groups compared to healthy controls.
- The study concluded that elevated serum IL-36γ levels are linked to the disease's activity and potentially serve as a biomarker for monitoring AS progression.
Potential clinical value of serum interleukin-41 levels in patients with acute gout.
Int Immunopharmacol
September 2023
Article Synopsis
- Gout is a common disease, and this study aimed to understand the levels of interleukin-41 (IL-41) in gout patients, which had not been previously reported.
- The research involved 81 participants, including patients with acute gout, those in remission, and healthy controls, using blood tests to measure IL-41 levels and analyze correlations with other health parameters.
- Findings showed that IL-41 levels were significantly higher in acute gout patients compared to healthy controls and suggested that IL-41 could serve as a diagnostic marker for acute gout, especially when combined with uric acid levels.
Objectives: Hashimoto's thyroiditis (HT) is the predominant cause of primary hypothyroidism. Interleukin (IL)-36γ is a member of the IL-36 family. Recently, IL-36γ was shown to possess proinflammatory properties in autoimmune diseases.
View Article and Find Full Text PDFBackground: Interleukin (IL)-41 is upregulated in the synovial tissue of rheumatoid arthritis (RA) patients, but its serum level has not been reported. The present study aimed to determine IL-41 expression in serum from RA patients and to clarify the relationships between IL-41 and disease-related parameters in RA patients.
Methods: The study included 46 RA patients and 32 healthy controls (HC).