Effects of functional training on physical and technical performance among the athletic population: a systematic review and narrative synthesis.

Background: The evidence indicates that functional training is beneficial for athletes' physical and technical performance. However, a systematic review of the effects of functional training on athletes' physical and technical performance is lacking. Therefore, this study uses a literature synthesis approach to evaluate the impact of functional training on the physical and technical performance of the athletic population and to extend and deepen the existing body of knowledge.

Online health information seeking behavior among breast cancer patients and survivors: a scoping review.

Purpose: This scoping review aims to summarize online health information seeking (OHIS) behavior among breast cancer patients and survivors, identify research gaps, and offer insights for future studies.

Methods: Following Arksey and O'Malley's framework, we conducted a review across PubMed, Web of Science, CINAHL, MEDLINE, Cochrane, Embase, CNKI, Wanfang Data, and SinoMed, covering literature from 1 January 2014 to 13 August 2023. A total of 1,368 articles were identified, with 33 meeting the inclusion criteria.

Anxiety and burnout in infectious disease nurses: the role of perceived stress and resilience.

Background: Nurses serving in infectious disease ward represent a distinct occupational group that has attracted considerable attention following epidemic outbreaks. However, prior to this study, no research had delved into the underlying mechanism linking anxiety to burnout symptoms among infectious disease nurses. This study aimed to explore investigate the association between anxiety and burnout among nurses working in such environments and scrutinized the mediating role of perceived stress and the moderating influence of resilience on the principal relationship.

Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.

Genome-wide association studies have identified approximately 200 genetic risk loci for breast cancer, but the causal variants and target genes are mostly unknown. We sought to fine-map all known breast cancer risk loci using genome-wide association study data from 172,737 female breast cancer cases and 242,009 controls of African, Asian and European ancestry. We identified 332 independent association signals for breast cancer risk, including 131 signals not reported previously, and for 50 of them, we narrowed the credible causal variants down to a single variant.

Latent profiles and determinants of postoperative sleep quality in elective surgery patients.

It is crucial to determine the potential subgroups of sleep disturbances in patients undergoing elective surgery based on the importance of symptom clusters and individual characteristics in order to develop targeted symptom management plans. This study explored the potential categories of postoperative sleep disturbances in patients undergoing elective surgery through latent profile analysis, and explored the influencing factors of each category. A total of 400 eligible elective surgery patients were included in the analysis, and three potential subgroups were identified: mild sleep disturbance group (c1 = 140,35.

Triboelectric tactile sensor for pressure and temperature sensing in high-temperature applications.

Skin-like sensors capable of detecting multiple stimuli simultaneously have great potential in cutting-edge human-machine interaction. However, realizing multimodal tactile recognition beyond human tactile perception still faces significant challenges. Here, an extreme environments-adaptive multimodal triboelectric sensor was developed, capable of detecting pressure/temperatures beyond the range of human perception.

Skillful seasonal predictions of continental East-Asian summer rainfall by integrating its spatio-temporal evolution.

Skillful seasonal climate prediction is critical for food and water security over the world's heavily populated regions, such as in continental East Asia. Current models, however, face significant difficulties in predicting the summer mean rainfall anomaly over continental East Asia, and forecasting rainfall spatiotemporal evolution presents an even greater challenge. Here, we benefit from integrating the spatiotemporal evolution of rainfall to identify the most crucial patterns intrinsic to continental East-Asian rainfall anomalies.

The behavioral characteristics of addiction and mental disorder caused by dextromethorphan abuse were analyzed in multiple dimensions.

Background: The aims of this study were to promote the rational use and supervision of dextromethorphan (DM). This study analyzed serious adverse events such as addiction and mental disorders caused by DM in Shenzhen and the behavioral characteristics of people suspected of abusing DM on the Internet.

Methods: Adverse drug reaction/event (ADR/E) reports from 2017 to 2023 were extracted from the National Pharmaceutical Adverse Reaction Monitoring System database.

Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study.

Background And Objective: Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, have emerged as promising diagnostic biomarkers for various tumours. This study aimed to identify a serum exosome ncRNA feature for enhancing GC diagnosis.

The community dynamic alterations mechanisms of traveling plastics in the Pearl River estuary with the salinity influence.

Most ocean plastics originate from terrestrial emissions, and the plastisphere on the plastics would alter during the traveling due to the significant differences in biological communities between freshwater and marine ecosystems. Microorganisms are influenced by the increasing salinity during traveling. To understand the contribution of plastic on the alteration in biological communities of plastisphere during traveling, this study investigated the alterations in microbial communities on plastics during the migration from freshwater to brackish water and saltwater.

Dual signal amplification in ECL biosensors: A novel approach for argonaute2 detection using SAHARA CRISPR-Cas12a technology.

Argonaute 2 (Ago2) is a crucial enzyme in the RNA interference (RNAi) pathway, essential for gene silencing via the cleavage of target messenger RNA (mRNA) mediated by microRNA (miRNA) or small interfering RNA (siRNA). The activity of Ago2 is a significant biomarker for various diseases, including cancer and viral infections, necessitating precise monitoring techniques. Traditional methods for detecting Ago2 activity are often cumbersome and lack the necessary sensitivity and specificity for low-abundance targets in complex samples.

Assessing the risk of TB progression: Advances in blood-based biomarker research.

This review addresses the significant advancements in the identification of blood-based prognostic biomarkers for tuberculosis (TB), highlighting the importance of early detection to prevent disease progression. The manuscript discusses various biomarker categories, including transcriptomic, proteomic, metabolomic, immune cell-based, cytokine-based, and antibody response-based markers, emphasizing their potential in predicting TB incidence. Despite promising results, practical application is hindered by high costs, technical complexities, and the need for extensive validation across diverse populations.

Switchable long-distance propagation of chiral magnonic edge states.

The coherent spin waves, magnons, can propagate without accompanying charge transports and Joule heat dissipation. Room-temperature and long-distance spin waves propagating within nanoscale spin channels are considered promising for integrated magnonic applications, but experimentally challenging. Here we report that long-distance propagation of chiral magnonic edge states can be achieved at room temperature in manganite thin films with long, antiferromagnetically coupled spin spirals (millimetre length) and low magnetic Gilbert damping (~3.

A rapid chemical reprogramming system to generate human pluripotent stem cells.

Chemical reprogramming enables the generation of human pluripotent stem (hCiPS) cells from somatic cells using small molecules, providing a promising strategy for regenerative medicine. However, the current method is time consuming, and some cell lines from different donors are resistant to chemical induction, limiting the utility of this approach. Here, we developed a fast reprogramming system capable of generating hCiPS cells in as few as 10 days.

Transition from multi-year La Niña to strong El Niño rare but increased under global warming.

El Niño-Southern Oscillation (ENSO) exhibits a strong asymmetry between warm El Niño and cold La Niña in amplitude and temporal evolution. An El Niño often leads to a heat discharge in the equatorial Pacific conducive to its rapid termination and transition to a La Niña, whereas a La Niña persists and recharges the equatorial Pacific for consecutive years preconditioning development of a subsequent El Niño, as occurred in 2020-2023. Whether the multiyear-long heat recharge increases the likelihood of a transition to a strong El Niño remains unknown.

Disentangling Sources of Momentum Fluctuations in Xe+Xe and Pb+Pb Collisions with the ATLAS Detector.

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

Measurement of CP Violation Observables in D^{+}→K^{-}K^{+}π^{+} Decays.

A search for violation of the charge-parity (CP) symmetry in the D^{+}→K^{-}K^{+}π^{+} decay is presented, with proton-proton collision data corresponding to an integrated luminosity of 5.4  fb^{-1}, collected at a center-of-mass energy of 13 TeV with the LHCb detector. A novel model-independent technique is used to compare the D^{+} and D^{-} phase-space distributions, with instrumental asymmetries subtracted using the D_{s}^{+}→K^{-}K^{+}π^{+} decay as a control channel.

Observation of Laser-Assisted Dynamic Interference by Attosecond Controlled Photoelectron Spectroscopy.

We have observed the laser-assisted dynamic interference in the electron spectra triggered by attosecond pulse trains. The fingerprints of finer interference fringes, much smaller than the laser photon energy, have been clearly identified experimentally. Our measurements are successfully reproduced by theoretical simulations utilizing the numerical solution to the time-dependent Schrödinger equation and the strong-field approximation.

Conjugated Linoleic Acid (CLA) Mitigates High-Fat Diet (HFD)-Induced Mammary Gland Development Impairment of Pubertal Mice via Regulating CD36 Palmitoylation and Downstream JNK-ERK Pathway.

Conjugated linoleic acid (CLA) is known for antiobesity. However, the role of CLA in regulating high-fat diet (HFD)-impaired pubertal mammary gland development remains undefined. Here, pubertal female mice and HC11 cells were treated with HFD or palmitic acid (PA), supplemented with or without CLA, respectively.

Thiol-Ene Click Chemistry: A General Strategy for Tuning the Properties of Vinylene-Linked Covalent Organic Frameworks.

Vinylene-linked Covalent Organic Frameworks (V-2D-COFs) are a class of promising porous organic materials that feature fully π-conjugated structures, high crystallinity, ultrahigh chemical stability, and extraordinary optoelectronic properties. However, the types of reactions and the availability of monomers for synthesizing linked COFs are considerably limited by the irreversibility of the C═C bond, and the complete π-conjugated structure restricts their in-depth research in hydrophilicity, membrane materials, and proton conductivity. Postsynthetic modification (PSM), which can avoid these problems by incorporating functional moieties into the predetermined framework, provides an alternative way to construct diverse V-2D-COFs.

Expanded Negative Electrostatic Network-Assisted Seawater Oxidation and High-Salinity Seawater Reutilization.

Coastal/offshore renewable energy sources combined with seawater splitting offer an attractive means for large-scale H electrosynthesis in the future. However, designing anodes proves rather challenging, as surface chlorine chemistry must be blocked, particularly at high current densities (). Additionally, waste seawater with increased salinity produced after long-term electrolysis would impair the whole process sustainability.

Ipsilateral restriction of chromosome movement along a centrosome, and apical-basal axis during the cell cycle.

Little is known about how distance between homologous chromosomes are controlled during the cell cycle. Here, we show that the distribution of centromere components display two discrete clusters placed to either side of the centrosome and apical/basal axis from prophase to G interphase. 4-Dimensional live cell imaging analysis of centromere and centrosome tracking reveals that centromeres oscillate largely within one cluster, but do not cross over to the other cluster.