Spatial relationships among offender, knife, and victim during slashing attacks: implications for crime scene reconstruction.

Background: The offender-victim spatial relationship is crucial in reconstructing a crime scene. The study aims to evaluate the spatial relationship of performing slashing attacks on a dummy using a Chinese kitchen knife, and thus to establish a scientific basis for crime scene reconstruction.

Methods: Twenty-four participants (12 males and 12 females) slashed a dummy's neck or chest using a kitchen knife, and the kinematic data were obtained using a three-dimensional motion capture system.

Voltage-gated sodium channels in cancer and their specific inhibitors.

Voltage-gated sodium channels (VGSCs) participate in generating and spreading action potentials in electrically excited cells such as neurons and muscle fibers. Abnormal expression of VGSCs has been observed in various types of tumors, while they are either not expressed or expressed at a low level in the matching normal tissue. Hence, this abnormal expression suggests that VGSCs confer some advantage or viability on tumor cells, making them a valuable indicator for identifying tumor cells.

Predicting vertical ground reaction force in rearfoot running: A wavelet neural network model and factor loading.

This study proposed a simple method for selecting input variables by factor loading and inputting these variables into a wavelet neural network (WNN) model to predict vertical ground reaction force (vGRF). The kinematic data and vGRF of 9 rearfoot strikers at 12, 14, and 16 km/h were collected using a motion capture system and an instrumented treadmill. The input variables were screened by factor loading and utilized to predict vGRF with the WNN.

Gain-of-function mutations in the catalytic domain of promote lung cancer malignant phenotypes via the MAPK/ERK signaling pathway.

Lung cancer is a lethal malignancy lacking effective therapies. Emerging evidence suggests that epigenetic enzyme mutations are closely related to the malignant phenotype of lung cancer. Here, we identified a series of gain-of-function mutations in the histone methyltransferase DOT1L.

Stride length mediates the correlation between movement coordination and sprint velocity.

In this study, we aimed to explore the correlation between movement coordination and sprint velocity and the mediating effects of stride length and frequency on this correlation. Thirty-two male college students (16 athletes and 16 non-athletes) participated in this study. Movement coordination was calculated using a vector coding method for intralimb (hip - knee, knee - ankle) and interlimb (hip - hip, knee - knee, ankle - ankle).

Characteristics of the Distance and Space Required for Knife Slashing Using a Motion Capture System.

Objectives: To investigate the relationship between the perpetrator's sex, victim's position and slashing location as well as anthropometric parameters on distance and space required for slashing, to provide the theoretical basis for the judgment of whether the crime scene was consistent with the criminal activity space.

Methods: The kinematics data of 12 male and 12 female subjects slashing the neck of standing and supine mannequins as well as the chest of the standing mannequins with a kitchen knife were obtained by using a 3D motion capture system. The relationship between the perpetrator's sex-victim's position, the perpetrator's sex-slashing location, and anthropometric parameters and the distance and space required for the slashing were analyzed by two-factor repeated measures ANOVA and Pearson correlation analysis respectively.

Gender-Specific Effects of 8-Week Multi-Modal Strength and Flexibility Training on Hamstring Flexibility and Strength.

The purpose of this study was to investigate the effects of multi-modal strength training or flexibility training on hamstring flexibility and strength in young males and females. A total of 20 male and 20 female college students (aged 18-24 years) participated in this study and were randomly assigned to either a multi-modal flexibility intervention group or strength intervention group. Passive straight leg raise and isokinetic strength test were performed before and after the intervention to determine flexibility and strength of the participants.

Biomechanical characteristics of slashing attack on different body parts of a dummy using a kitchen knife.

Background: Slashing attack is one of the most common ways of committing a homicide. The purpose of this study was to evaluate the biomechanical characteristics of slashing different body parts of a dummy by young males and females using a Chinese kitchen knife and thus provide scientific evidence for criminal investigations and court trials.

Methods: A total of 12 male and 12 female college students participated in this study.

Effects of integrative neuromuscular training intervention on physical performance in elite female table tennis players: A randomized controlled trial.

Objectives: To investigate the effects of integrative neuromuscular training (INT) on physical performance in elite female table tennis players.

Methods: Twenty-four Chinese elite female table tennis players were randomized into either INT (n = 12) group or control group (CON; n = 12). INT group performed four INT sessions every week for 8 weeks, while CON group performed traditional physical fitness training.

Effects of motor skill level and speed on movement variability during running.

Variability in movement is an informative biological feature. This study aimed to examine the effects of motor skill level and running speed on movement variability. Twenty-nine male college students (fourteen athletes and fifteen non-athletes) participated in this study.

Effects of flexibility and strength training on peak hamstring musculotendinous strains during sprinting.

Background: Hamstring injury is one of the most common injuries in sports involving sprinting. Hamstring flexibility and strength are often considered to be modifiable risk factors in hamstring injury. Understanding the effects of hamstring flexibility or strength training on the biomechanics of the hamstring muscles during sprinting could assist in improving prevention strategies and rehabilitation related to these injuries.

Effects of flexibility and strength interventions on optimal lengths of hamstring muscle-tendon units.

Objectives: The aim of the present study was to determine the effects of altering both hamstring flexibility and strength on hamstring optimal lengths.

Design: Controlled laboratory study.

Methods: A total of 20 male and 20 female college students (aged 18-24 years) participated in this study and were randomly assigned to either a flexibility intervention group or a strength intervention group.