[Clinical effect of acupuncture based on the specific response of -well point for intractable insomnia: a randomized controlled trial].

Objective: To evaluate clinical effect and safety on the basis of detecting the specific response of -well point in treatment of intractable insomnia with acupuncture by meridian differentiation.

Methods: Sixty-four patients with intractable insomnia were randomized into an observation group (32 cases, 1 case dropped out and 1 case was eliminated) and a control group (32 cases, 1 case was eliminated). In the observation group, the meridian imbalance value detected at the -well point was taken as the evidence so that the corresponding -source and back- points were stimulated with acupuncture.

Effect of vitamin B, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis.

Objectives: The objective of the current study is to compare the treatment effects of different vitamins on essential hypertension to provide an initial basis for developing evidence-based practices.

Design: Systematic review and network meta-analysis.

Data Sources: Five electronic databases (PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials and ClinicalTrials.

The Critical Effect of Bile Acids in Atherosclerosis.

Atherosclerosis (AS) is one of the most common cardiovascular diseases and is the leading cause of arteriosclerotic cardiovascular disease. Bile acids are not only the products of cholesterol metabolism, but also an important class of signaling molecules. Bile acids exert their biological effects through the bile acid receptor signaling pathways.