Identifying important microbial biomarkers for the diagnosis of colon cancer using a random forest approach.

Colon cancer is one of the most common cancers, with 30-50 % of patients returning or metastasizing within 5 years of treatment. Increasingly, researchers have highlighted the influence of microbes on cancer malignant activity, while no studies have explored the relationship between colon cancer and the microbes in tumors. Here, we used tissue and blood samples from 67 colon cancer patients to identify pathogenic microorganisms associated with the diagnosis and prediction of colon cancer and evaluate the predictive performance of each pathogenic marker and its combination based on the next-generation sequencing data by using random forest algorithms.

PEX26 Functions as a Metastasis Suppressor in Colorectal Cancer.

Background/aims: Aberrant Peroxisomal Biogenesis Factor 26 (PEX26) occurs in multiple cell process. However, the role of PEX26 in colorectal cancer (CRC) development remains unknown. We aimed to study PEX26 expression, regulation, and function in CRC cells.

Combined application of biochar and nitrogen fertilizer promotes the activity of starch metabolism enzymes and the expression of related genes in rice in a dual cropping system.

Background: Overuse of chemical fertilizer highly influences grain filling rate and quality of rice grain. Biochar is well known for improving plant growth and grain yield under lower chemical fertilization. Therefore field trials were conducted in the early and late seasons of 2019 at Guangxi University, China to investigate the effects of combined biochar (B) and nitrogen (N) application on rice yield and yield components.

Impact of fertilization with reducing in nitrogen and phosphorous application on growth, yield and biomass accumulation of rice ( L.) under a dual cropping system.

The current farming system in China is heavily reliant on synthetic fertilizers, which adversely affect soil quality and crop production. Therefore, the aim of this study was to assess the effect of different nitrogen (N) and phosphorous (P) fertilizer application rate on the growth, yield, and yield components of rice cultivars in the Binyang, Beiliu and Liucheng sites of southern China in the early (March to July) and late season (August to December). The study consisted of three fertilization regimes-CK (NP); NP (180 kg N + 90 kg PO ha) and NP (90 kg N ha + 45 kg PO)-conducted at each of three different experimental sites with four cultivars (Baixang 139, Y Liangyou 1, Guiyu 9, and Teyou 582).

Automated measurement of hip-knee-ankle angle on the unilateral lower limb X-rays using deep learning.

Significant inherent extra-articular varus angulation is associated with abnormal postoperative hip-knee-ankle (HKA) angle. At present, HKA is manually measured by orthopedic surgeons and it increases the doctors' workload. To automatically determine HKA, a deep learning-based automated method for measuring HKA on the unilateral lower limb X-rays was developed and validated.

Combined application of biochar and nitrogen fertilizer improves rice yield, microbial activity and N-metabolism in a pot experiment.

The excessive use of synthetic nitrogen (N) fertilizers in rice ( L.) has resulted in high N loss, soil degradation, and environmental pollution in a changing climate. Soil biochar amendment is proposed as a climate change mitigation tool that supports carbon sequestration and reduces N losses and greenhouse gas (GHG) emissions from the soil.