Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2.

Advanced mRNA vaccines play vital roles against SARS-CoV-2. However, most current mRNA delivery platforms need to be stored at -20 °C or -70 °C due to their poor stability, which severely restricts their availability. Herein, we develop a lyophilization technique to prepare SARS-CoV-2 mRNA-lipid nanoparticle vaccines with long-term thermostability.

Measurement of China's Green Total Factor Productivity Introducing Human Capital Composition.

In the face of resource and environmental problems caused by extensive economic development, China has put forward a green development strategy. Scientific measurement and analysis of green total factor productivity (GTFP) is of great significance for achieving high-quality economic development. By introducing the human capital composition, including education, health, scientific research, and training, this paper study adopts the Slack Based Measure-Global Malmquist-Luenberger (SBM-GML) index to re-measure the GTFP and its decomposition of 30 provinces, municipalities, and autonomous regions in China from 2000 to 2019.

A Random Forest Method for Identifying the Effectiveness of Innovation Factor Allocation.

This paper makes a new attempt to identify the effectiveness of innovation factor allocation with a random forest method. This method avoids the evaluation bias of the relative effectiveness caused by the noneffective selection of production frontier in the nonparametric DEA method. It does not refer to other optimal subjects but shifts the focus to the judgment of its own effectiveness.