CT-guided radiofrequency neurotomy (RFN) of bilateral T3-4 sympathetic chain combined with bilateral L3 sympathetic ganglion in patient with palmar hyperhidrosis.

Palmoplantar hyperhidrosis is a functional disease with an unknown pathogenesis, making it challenging to find a lasting and effective treatment. This article reports a case of a 43-year-old patient with palmoplantar hyperhidrosis treated with computed tomography (CT)-guided radiofrequency neurotomy (RFN) of bilateral T3-4 sympathetic chain combined with bilateral L3 sympathetic ganglion. The optimal puncture level and skin entry point were selected, and measurements were taken using a CT tool to determine needle depth, angle, and distance from the midline.

Efficacy and safety of radiofrequency ablation versus surgical sympathectomy in palmar hyperhidrosis.

Radiofrequency ablation (RFA) comparative efficacy of treatments using video-assisted thoracoscopic sympathectomy (VATS) in the long term remains uncertain in patients with palmar hyperhidrosis (PHH). This study aimed to compare the efficacy and safety of RFA and VATS in patients with PHH. We recruited patients aged ≥ 14 years with diagnosed PHH from 14 centres in China.

YBX1 Promotes MSC Osteogenic Differentiation by Activating the PI3K/AKT Pathway.

Introduction: Bone metabolism has an essential role in bone disease, but its specific mechanism remains unclear. Y-Box Binding Protein 1 (YBX1) is a gene with broad nucleic acid binding properties, which encodes a highly conserved cold shock domain protein. Previous studies have shown that YBX1 is closely related to cell differentiation.

The impact of CRMP4 SUMOylation on the Cav1.2 interaction, neurite outgrowth and thermal pain sensitivity.

Collapsin response mediator protein 4 (CRMP4) is critical for neuronal development. However, whether CRMP4 could be SUMOylated and how the SUMOylation regulates the interaction with the L-type voltage-gated calcium channel (Cav1.2), neurite outgrowth, and thermal pain sensitivity remain to be elucidated.