[Effects of yixintong on regulating cellular calcium channels].

Objective: To explore the protecting mechanism of Yixintong for heart ischemia-reperfusion injury at cellular and subcellular levels, by observing the effects of Yixintong on three kinds of calcium channels.

Method: The effects of Yixintong on Ca2+ influx on leak calcium channel, receptor-operationg calcium channel (ROC) and pulse-dependent calcium channel (PDC) were observed respectively, by using rat aortic smooth muscle cell and radioactive 45Ca technique.

Result: Yixintong has no effects on leak calcium channel, but can inhibit the Ca2+ influx in ROC and PDC significantly.