A meta-analysis of the effect of CYP2D6 polymorphism on the pharmacokinetics and pharmacodynamics of metoprolol .

Objective: To conduct a meta-analysis on the effect of CYP2D6 polymorphism on the pharmacokinetics and pharmacodynamics of metoprolol.

Methods: A systematic review and meta-analysis of studies on the effect of CYP2D6 polymorphism on metoprolol pharmacokinetics and pharmacodynamics was performed by using the China national knowledge infrastructure (CNKI), database for Chinese technical periodicals (VIP), Wanfang, and PubMed databases up to the end of January 2015. Review Manager 5.

[Application of Terahertz Spectroscopy in the Detection of Chinese Medicine Processed Drugs of Rhubarb].

The changes of composition of the processed traditional Chinese medicine will affect the curative effect of drug, such as the four kinds of processed rhubarb. The characteristics data of each rhubarb was measured with terahertz spectroscopy system and analyzed with chemometrics, and the spectral data was classified according to the category of rhubarb. The substance components of anthraquinone and tannins make changes in processed rhubarb by thin layer chromatography (TLC).