[Prevention of rupture of atherosclerotic plaque by Candesartan in rabbit model].

Objective: To evaluate Candesartan therapeutic effect against atherosclerotic plaque rupture and to explore the related mechanisms.

Methods: Thirty-four New Zealand White male rabbits were randomly divided into three groups: the control group, the model control group and the Candesartan intervention group. The control group rabbits were fed with a normal diet.