Fads2b Plays a Dominant Role in ∆6/∆5 Desaturation Activities Compared with Fads2a in Common Carp ().

Highly unsaturated fatty acids (HUFAs) are essential for mammalian health, development and growth. However, most mammals, including humans, are incapable of synthesizing n-6 and n-3 HUFAs. Fish can convert C18 unsaturated fatty acids into n-6 and n-3 HUFAs via fatty acid desaturase (Fads), in which Fads2 is a key enzyme in HUFA biosynthesis.

Role of vascular endothelial growth factor B in nonalcoholic fatty liver disease and its potential value.

Nonalcoholic fatty liver disease (NAFLD) refers to fatty liver disease caused by liver injury factors other than alcohol. The disease is characterized by diffuse fat infiltration, including simple steatosis (no inflammatory fat deposition), nonalcoholic fatty hepatitis, liver fibrosis, and so on, which may cause liver cirrhosis, liver failure, and even liver cancer in the later stage of disease progression. At present, the pathogenesis of NAFLD is still being studied.

Dominant Elongase Activity of but Higher Expression of in Common Carp ().

Most diploid freshwater and marine fish encode one elongase, having substrate specificity and activities towards C18, C20 and C22 polyunsaturated fatty acids (PUFAs). The allo-tetraploid common carp is hypothesized to encode two duplicated genes. How these two genes adapt to coordinate the PUFA biosynthesis through elongase function and expression divergence requires elucidation.

Honeycomb-like 3D carbon skeletons with embedded phosphorus-rich phosphide nanoparticles as advanced anodes for lithium-ion batteries.

Phosphorus-rich iron phosphides (FeP) have been regarded as excellent anode candidates for lithium storage owing to their low cost, high natural abundance, high theoretical capacity, and reasonable redox potential. However, FeP suffers from a few challenging problems such as low reversibility, fast capacity degradation, and big volume variation. Herein, we have designed and synthesized a 3D honeycomb-like carbon skeleton with embedded FeP nanoparticles (denoted as FeP NPs@CK), which can significantly promote the kinetics and maintain the structural stability during the cycling, resulting in an excellent electrochemical performance reflected by high reversibility and long-term cycling stability.

A Dendrite-Free Lithium-Metal Anode Enabled by Designed Ultrathin MgF Nanosheets Encapsulated Inside Nitrogen-Doped Graphene-Like Hollow Nanospheres.

Uncontrolled lithium dendrite growth and dramatic volume change during cycling have long been severely impeding the practical applications of Li metal as the ultimate anode. In this work, ultrathin MgF nanosheets encapsulated inside nitrogen-doped graphene-like hollow nanospheres (MgF NSs@NGHSs) are ingeniously fabricated to address these problems by a perfect combination of atomic layer deposition and chemical vapor deposition. The uniform and continuous Li-Mg solid-solution inner layer formed by the MgF nanosheets can reduce the nucleation overpotential and induce selective deposition of Li into the cavities of the NGHSs.

Chromosome-level genome assembly of golden pompano (Trachinotus ovatus) in the family Carangidae.

Golden pompano (Trachinotus ovatus), a marine fish in the Carangidae family, has a wide geographical distribution and adapts to severe environmental rigours. It is also an economically valuable aquaculture fish. To understand the genetic mechanism of adaption to environmental rigours and improve the production in aquaculture, we assembled its genome.

LR_Gapcloser: a tiling path-based gap closer that uses long reads to complete genome assembly.

Background: Completing a genome is an important goal of genome assembly. However, many assemblies, including reference assemblies, are unfinished and have a number of gaps. Long reads obtained from third-generation sequencing (TGS) platforms can help close these gaps and improve assembly contiguity.

Whole genome sequencing yields the complete mitogenome of , an indicator species of the Arctic ecosystem.

is an important indicator species to study the state of the Arctic ecosystem. The mitochondrial genome of is 15,956 bp in length and encodes 13 protein-coding genes. The phylogenetic tree of eleven shrimps revealed that belonged to family and was closely related to This mitogenome will be of significance to study the Arctic ecosystem state and perform the resource protection of this species.

Characterization and phylogenetic analysis of the mitochondrial genome of , a national-protected fish in China.

is a national key protected fish in China. The mitochondrial genome of is 16,578 bp in length and includes two ribosomal RNA genes, 22 tRNA genes, and 13 protein-coding genes. The phylogenetic analysis showed that belongs to family and is closely related to other fish.

Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity.

The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions.

High mobility group B proteins regulate mesoderm formation and dorsoventral patterning during zebrafish and Xenopus early development.

The high mobility group (HMG) proteins constitute a superfamily of nuclear proteins that regulate the expression of a wide range of genes through architectural remodeling of the chromatin structure, and the formation of multiple protein complexes on promoter/enhancer regions, but their function in germ layer specification during early development is not clear. Here we show that hmgb genes regulate mesoderm formation and dorsoventral patterning both in zebrafish and Xenopus early embryos. Overexpression of hmgb3 blocks the expression of the pan-mesoderm gene no tail/Xbra and other ventrolateral mesoderm genes, and results in embryos with shortened anteroposterior axis, while overexpression of hmgb3EnR, which contains the engrailed repressor domain, most potently repressed no tail expression and mesoderm formation.