Publications by authors named "Shang-Fu Li"

Article Synopsis
  • Herbal medicine Sanqi (SQ), derived from Panax notoginseng (PNS), shows promise in combating diabetes and obesity, but detailed studies on its signaling networks are limited.
  • Researchers used a systems biology approach with RNA and miRNA sequencing to identify key pathways and genes related to metabolic disorders like insulin resistance.
  • The study found that PNS treatment increased levels of certain protective proteins while decreasing harmful microRNAs, suggesting a mechanism for how PNS helps regulate cellular functions in metabolic issues.
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Gastric cancer remains a malignant disease of the digestive tract with high mortality and morbidity worldwide. However, due to its complex pathological mechanisms and lack of effective clinical therapies, the survival rate of patients after receiving treatment is not satisfactory. A increasing number of studies have focused on cancer stem cells and their regulatory properties.

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We report here a simple and rapid method of separation, identification and quantification of tetrodotoxin (TTX) and its analogs in partially purified extract by LC-MS. Except for the main component calibration of individual components was not necessary. TTX and four of its analogs in the puffer fish extract were identified and quantified.

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