Publications by authors named "Shang-Ao Gong"
Article Synopsis
- The study investigates the use of Diffusion Kurtosis Imaging (DKI) to assess renal interstitial fibrosis caused by hyperuricemia in a rat model.
- Rats were divided into groups for different treatments and DKI measurements were taken at various intervals to analyze kidney tissue changes and fibrosis.
- Results showed that DKI could effectively monitor fibrosis levels, with certain imaging indicators correlating with histopathological findings, suggesting DKI is a useful non-invasive method for renal assessment.
Objectives: To validate the feasibility of intravoxel incoherent motion imaging (IVIM) for monitoring renal injury and uric acid-lowering efficacy in a rat model of hyperuricaemia.
Methods: A total of 92 rats were analysed and categorized into 4 groups: control (CON), hyperuricaemia (HUA), allopurinol intervention (ALL), and combined intervention (COM). Eight rats were randomly selected from each group and underwent IVIM scanning on days 0, 1, 3, 5, 7, and 9.