Publications by authors named "Shang Wei Zuo"

The associations between hyperhomocysteinaemia (HHcy), methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, and abdominal aortic aneurysm (AAA) remain controversial, with only few studies focused on these associations within the Chinese population. We performed subgroup and interaction analyses in a Chinese Han population to investigate these associations. In all, 155 AAA patients and 310 control subjects were evaluated for serum total homocysteine levels and MTHFR C677T polymorphisms.

View Article and Find Full Text PDF

Objective: To examine the potential influence factors of abdominal aortic aneurysm (AAA).

Methods: A 1:2 pair-matched, case-control study was conducted from July 2011 to December 2012. A pair was composed of one AAA patient recruited from the Vascular Surgery Department, Chinese PLA General Hospital and two gender- and age-matched non-AAA subjects, one from the same hospital and the other from the community in Fangshan District in Beijing.

View Article and Find Full Text PDF
Article Synopsis
  • * Researchers synthesized a gene coding for tropoelastin and used adenoviral vectors to introduce this gene into vascular smooth muscle cells from rats, followed by various analyses to observe the effects on elastic fiber formation.
  • * Results showed that the introduction of the elastin gene significantly increased elastic fiber regeneration in the aortic walls and led to a reduction in aneurysm diameter by about 23%.
View Article and Find Full Text PDF