Comparative Transcriptome Analysis Reveals Mechanisms of Differential Salinity Tolerance Between and .

Background: and have obvious morphological features and strongly tolerate saline-alkali environments. However, the mechanisms that lead to the differences in saline-alkali tolerance between them remain unclear.

Methods: In this study, we employed comparative transcriptome analysis to investigate and under saline-alkali stress.

Controllable Droplet Splitting with Parallel-Plate Optoelectrowetting Chips.

Recent advances in microfluidic technology highlight electrowetting for its programmability and precision. However, traditional electrowetting chips face limitations in scalability due to fixed electrode sizes. Optoelectrowetting (OEW) offers a solution with light-controlled virtual electrodes, but droplet splitting remains challenging.

Mass load and source apportionment of pharmaceutical and personal care product in the Wuhan section of the Yangtze River, China.

Given the limited research on pharmaceuticals and personal care products (PPCPs) in the Wuhan section of the Yangtze River (WYR), this work investigated the distribution of 15 PPCPs in this region, assessed their ecological risks and annual fluxes. It was further to analyze the levels of indicator sucralose in the WYR to understand the sources of PPCPs. The results showed the average concentrations were 143.

Unc5b prevents macrophage-derived foam cell migration and promotes atherosclerotic development via the P53-cuproptosis signaling pathway.

Background: Atherosclerosis involves the buildup of macrophage-derived foam cells in the arterial intima. Facilitating the egress of these cells from plaques can significantly slow disease progression. The transmembrane receptor Unc5b, a vascular-specific axon guidance receptor, is upregulated in foam cells, and inhibits their migration from the plaques.

PKM2-mediated STAT3 phosphorylation promotes acute liver failure via regulating NLRP3-dependent pyroptosis.

Acute liver failure (ALF) is a life-threatening clinical syndrome characterized by high-grade inflammation and multi-organ failure. Our previous study shows that targeting the M2 isoform of pyruvate kinase (PKM2) to inhibit macrophage inflammation may be a promising strategy for ALF treatment. however, the mechanism by which PKM2 regulates the inflammatory response is unclear.

[Mechanism of kaempferol on intervertebral disc degeneration based on p38 MAPK signaling pathway].

This study investigated the mechanism by which kaempferol(KAE) affected intervertebral disc degeneration(IDD) through the p38 mitogen-activated protein kinase(p38 MAPK) signaling pathway. Rats were randomly divided into five groups: control group, model group, low-dose KAE group, medium-dose KAE group, and high-dose KAE group. An IDD model was established by needle puncture of the caudal intervertebral discs.

Unraveling the hidden link: neuroticism as a risk factor for upper urinary tract calculi-insights from Mendelian randomization analysis.

Background: Upper urinary tract calculi (UUTC) are major risk factors for renal insufficiency and nephrectomy with psychological distress, notably depression and anxiety, being common among affected patients. Depression and anxiety are associated with heightened neuroticism. Individuals with neuroticism frequently exhibit a range of urological disorders.

Effects of Ultrasound-Assisted Treatment on Physicochemical Properties and Biological Activities of Polysaccharides from .

The aim of this study was to investigate the effect of ultrasonic treatment on the physicochemical properties and bioactivities of polysaccharides from samples (SPs) extracted with different solvents. The alkali-assisted extraction of polysaccharide (SPA), acid-assisted extraction of polysaccharides from (SPB), and hot water extraction of polysaccharides (SPCs) were perofrmed on . Ultrasonic treatment was performed with the SPA, SPB, and SPC in turn, and named USPA, USPB, and UPSC, respectively.

Six new species of Chelipoda (Diptera: Empididae) from Shennongjia, China.

Only three species of Chelipoda were known to occur in Shennongjia National Nature Reserve. The following six species are described as new to science: C. biancistroides sp.

Double-Oxidant-Induced Slurry Reaction Mechanism and Performance on Chemical Mechanical Polishing of 4H-SiC (0001) Wafer.

Single-oxidant slurries are prevalently utilized in chemical and mechanical polishing (CMP) of 4H-SiC crystal. Nevertheless, it is a challenge to achieve a high material removal rate (MRR) and surface quality using single oxidant slurries to meet the needs of global planarization and damage-free nanoscale surface processing of SiC wafers. To solve this challenge, a novel method is proposed for SiC CMP processing using the double oxidant slurry.

ZnO quantum dots reduce acquisition of huanglongbing pathogen by Diaphorina citri.

Background: Diaphorina citri Kuwayama is the main vector of the Huanglongbing (HLB) pathogen Candidatus Liberibacter asiaticus (CLas). Therefore, reducing CLas acquisition by D. citri is crucial for controlling the spread of HLB.

An oxygen-scavenging system without impact on DNA mechanical properties in single-molecule fluorescence experiments.

Oxygen scavenging systems (OSSs) are critical for dye stability in single-molecule fluorescence (SMF) experiments. However, the commonly used protocatechuic acid (PCA)/protocatechuate-3,4-dioxygenase (PCD) OSS alters DNA mechanical properties, limiting its applicability. To address this limitation, we examine the bilirubin oxidase (BOD) OSS, which had not been previously used in single-molecule experiments, alongside the pyranose oxidase and catalase (POC) OSS.

Simultaneous Development of Antiferromagnetism and Local Symmetry Breaking in a Kagome Magnet (CoFe)Sn.

CoSn and FeSn, two kagome-lattice metals, have recently attracted significant attention as hosts of electronic flat bands and emergent physical properties. However, current understandings of their physical properties are limited to knowledge of the average crystal structure. Here, we report the Fe-doping induced coemergence of the antiferromagentic (AFM) order and local symmetry breaking in (CoFe)Sn.

Multi-Omics Exploration of the Role of PTGS2 as a Hub Gene in Ferroptosis Within the Artery of Takayasu Arteritis.

Introduction: Takayasu arteritis (TAK) is an autoimmune disease affecting the aorta and its branches. Despite anti-inflammatory treatments, some patients require surgical vascular reconstruction due to rapid disease progression. The mechanisms behind persistent inflammation are unclear due to a lack of arterial samples.

Engineering Charge Transfer Characteristics in ZnO NRs/AgO NPs p-n Heterojunctions: Toward Highly Efficient and Recyclable Photocatalysts.

Staggered gap p-n heterojunction ZnO nanorods/AgO nanoparticles, a paradigm of photocatalysts, were developed via engineering the hydrothermal and coprecipitation method. Under simulated sunlight, the photocatalytic characteristics of ZnO/AgO(Zn/A) heterojunctions with varying mole ratios (from 8:1 to 8:4, named Zn/A-1-Zn/A-4) were systematically evaluated through the degradation of methylene blue (MB). The influence of key experimental variables, including photocatalyst concentration, MB concentration, and solution pH, on the photocatalyst performance was further analyzed.

Gradient ethanol extracts of Coreopsis tinctoria buds: Chemical and in vitro fermentation characteristics.

Coreopsis tinctoria buds grow at high altitudes and have unique medicinal and health effects. This study focused on the chemical components of gradient ethanol extracts of Coreopsis tinctoria buds and their impact on the gut microbiota and its metabolites. UPLC-Q-Exactive-MS results disclosed the presence of 24 distinct chemicals in the extracts, marein, and quercetin-3-β-D-glucoside as the predominant antioxidants.

Study of prediction model for high-grade meningioma using fractal geometry combined with radiological features.

Purpose: To establish a prediction model combining fractal geometry and radiological features, which consider the complexity of tumour morphology advancing beyond the limitations of previous models.

Methods: A total of 227 patients at the First Affiliated Hospital of Harbin Medical University from July 2021 to November 2023 were included. Fractal geometry was calculated and the radiomics features were extracted from regions of interest (ROIs).

Establishment of a high-sensitivity time-resolved fluorescence immunoassay with PLA2R-IgG1 antibody and its clinical application in idiopathic membranous nephropathy prognosis.

Introduction: The objective of this study was to develop a highly sensitive time-resolved fluorescence immunoassay (TRFIA) method to detect phospholipase A2 receptor (PLA2R)-IgG1 antibodies and evaluate its clinical relevance in predicting the prognosis of individuals with idiopathic membranous nephropathy (IMN).

Materials And Methods: A three-step indirect TRFIA method was established using a PLA2R antigen-coated microtiter plate to capture PLA2R-IgG antibodies, followed by detection using mouse anti-human IgG1 and Eu-labeled goat anti-mouse IgG antibodies. This method was applied to the initial serum of 56 patients with PLA2R-IMN to investigate the clinical value of PLA2R-IgG1 antibody levels in predicting IMN prognosis.

GSSF: Generalized Structural Sparse Function for Deep Cross-Modal Metric Learning.

Cross-modal metric learning is a prominent research topic that bridges the semantic heterogeneity between vision and language. Existing methods frequently utilize simple cosine or complex distance metrics to transform the pairwise features into a similarity score, which suffers from an inadequate or inefficient capability for distance measurements. Consequently, we propose a Generalized Structural Sparse Function to dynamically capture thorough and powerful relationships across modalities for pair-wise similarity learning while remaining concise but efficient.

Multidentate Chelating Ligands Enable High-Performance Zinc-Bromine Flow Batteries.

Zinc bromine flow battery (ZBFB) is a promising battery technology for stationary energy storage. However, challenges specific to zinc anodes must be resolved, including zinc dendritic growth, hydrogen evolution reaction, and the occurrence of "dead zinc". Traditional additives suppress side reactions and zinc dendrite formation by altering the solvation structure of Zn and adsorbing onto the zinc surface through only a limited number of zincophilic sites, resulting in weak adsorption on zinc metal and potential inability to simultaneously optimize the solvation structure of zinc ions.

Optimization of and experimentation with a bifurcated swing tube strip fertilizer spreading device based on MBD-DEM coupling.

Introduction: To improve the utilization rate of fertilizers, realize the precise spreading of fertilizers in controllable strips, and ensure the uniformity of fertilizer spreading in both longitudinal and transversal directions, a bifurcated swing tube fertilizer spreading device driven by a spatial hammer pendulum crank mechanism was designed.

Methods: First, the drive mechanism was designed based on the cylindrical pair of the mechanism. A mathematical model pendulum equation was used to design the swing tube, and the equation of motion of fertilizer particles was established by analyzing the motion and force of fertilizer particles in fertilizer spreading.

Effect of Extraction Methods on Chemical Characteristics and Bioactivity of cv. Fubaiju Extracts.

cv. Fubaiju (CMF) is regarded as one of the three most renowned varieties of white in China, and different extraction methods have significant effects on its composition and activities. Therefore, six extractions were used in this study to assess the effects on extracts.

A systematic mapping study on gamification within information security awareness programs.

Information security awareness (ISA) has become a vital issue for organizations, as security breaches are usually attributed to human errors. ISP programs are effective ways to educate employees and enhance their information security knowledge. Gamification is a new concept in the area of ISA programs and it has been proven to be one of the most effective and proper ISA methods in both the private and public sectors.