Analysis of Spinal-Pelvic Sagittal Plane Parameters in Patients with Lumbar Vertebral Posterior Ring Apophysis Separation.

Objective: To investigate the characteristics of the spinal-pelvic sagittal sequence in patients with lumbar vertebral posterior ring apophysis separation (PRAS).

Methods: A retrospective analysis was conducted on 119 hospitalized patients with PRAS, and 119 adults without symptoms of low back and leg pain were selected as the control. General data and spinal-pelvic sagittal parameters were collected and analyzed.

A three-dimensional discrete element model of triaxial tests based on a new flexible membrane boundary.

Based on a new elastic clump model, a flexible membrane is proposed for the discrete element numerical simulations of triaxial tests. Conversional triaxial tests of sandstone under the confining pressures of 2 MPa and 8 MPa were carried out, in order to validate the effectiveness of the proposed numerical simulation method. The numerical model is validated by comparing the numerical results with the test results.

Wound Healing Potential of the Standardized Extract of Boswellia serrata on Experimental Diabetic Foot Ulcer via Inhibition of Inflammatory, Angiogenetic and Apoptotic Markers.

The aim of the present study was to evaluate the wound healing potential and possible mechanism of action of the standardized extract of against the experimental model of diabetic foot ulcer. -Boswellic acid was isolated from the standardized extract of and characterized (HPLC, H-NMR, C-NMR, ESI-MS). Diabetes was induced in Sprague-Dawley rats by streptozotocin (55 mg/kg, i.

The establishment and biological assessment of a whole tissue-engineered intervertebral disc with PBST fibers and a chitosan hydrogel in vitro and in vivo.

Intervertebral disc (IVD) degeneration (IDD) is the main cause of low back pain in the clinic. In the advanced stage of IDD, both cell transplantation and gene therapy have obvious limitations. At this stage, tissue-engineered IVDs (TE-IVDs) provide new hope for the treatment of this disease.

Novel nano-microspheres containing chitosan, hyaluronic acid, and chondroitin sulfate deliver growth and differentiation factor-5 plasmid for osteoarthritis gene therapy.

Objective: To construct a novel non-viral vector loaded with growth and differentiation factor-5 (GDF-5) plasmid using chitosan, hyaluronic acid, and chondroitin sulfate for osteoarthritis (OA) gene therapy.

Methods: Nano-microspheres (NMPs) were prepared by mixing chitosan, hyaluronic acid, and chondroitin sulfate. GDF-5 plasmid was encapsulated in the NMPs through electrostatic adsorption.

Factors influencing diagnosis of colorectal cancer: a hospital-based survey in China.

Objective: To investigate the diagnostic status of colorectal cancer (CRC) and the influence of early diagnosis and cancer stage in a tertiary care hospital in China.

Methods: Face-to-face interviews were conducted in 364 consecutive CRC patients who had never participated in CRC screening. Initial symptoms, diagnosis and treatment delay were determined using a questionnaire.