Publications by authors named "Shane Desfor"
Article Synopsis
- * Using an EAE mouse model, researchers tracked the progression of visual impairment during different disease stages, finding significant demyelination and axon damage over time.
- * Analysis showed that untreated early inflammation can lead to severe, lasting damage to the optic nerves, providing insights into the worsening visual dysfunction experienced in MS.
Moorea producens JHB, a Jamaican strain of tropical filamentous marine cyanobacteria, has been extensively studied by traditional natural products techniques. These previous bioassay and structure guided isolations led to the discovery of two exciting classes of natural products, hectochlorin (1) and jamaicamides A (2) and B (3). In the current study, mass spectrometry-based 'molecular networking' was used to visualize the metabolome of Moorea producens JHB, and both guided and enhanced the isolation workflow, revealing additional metabolites in these compound classes.
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