Synopsis of recent research by authors named "Shandong Jian"
Shandong Jian's recent research focuses on the development of peptide-based therapies for cancer treatment, utilizing innovative drug delivery systems and modifications to enhance therapeutic efficacy.
His work includes the identification of the disintegrin Accutin from snake venom, which demonstrates significant anti-tumor migration properties by inhibiting epithelial-mesenchymal transition (EMT) and specific signaling pathways.
Jian has also explored fatty acid modifications and glycosylation of anticancer peptides to improve their cytotoxicity and therapeutic targeting, showcasing the versatility and effectiveness of peptide-based drug delivery systems in combatting cancer metastasis.