Application of covered stent implantation combined with radical tumor resection in advanced head and neck squamous cell carcinoma involving the carotid artery: a comparative study with historical literature.

Background: Studies have shown that carotid artery reconstruction results in the best overall survival (OS) in Advanced Head and Neck Squamous Cell Carcinoma involving the Carotid Artery (AHNSCC-CA).

Aims: The purpose of this study was to evaluate the efficacy of covered stent implantation combined with radical tumor resection and to compare and analyze the historical literature on conventional carotid artery resection and reconstruction.

Materials And Methods: A total of 68 patients with AHNSCC-CA were included in this study.

Surgical Management Strategies for Carotid Artery Invasion by Head and Neck Cancer: Ligation Versus Reconstruction.

Objective: Whether ligation or reconstruction should be performed after radical resection of the tumor and carotid artery in patients with head and neck cancers invading the carotid artery (HNC-CA) has been controversial. This paper provides a review and meta-analysis of the efficacy of these 2 modalities.

Data Sources: PubMed, Cochrane, Web of Science, Scopus, and Ovid databases were searched through August 2023.

Recurrence and malignant transformation of laryngeal leukoplakia treated with CO laser: A systematic review and meta-analysis.

Background: Laryngeal leukoplakia (LL) is a white lesion with high potential of recurrence and malignant transformation. Currently, CO laser has become the primary surgical treatment for LL, and the recurrence and malignant transformation rates after treatment vary widely.

Objective: We performed a systematic review and meta-analysis dedicated to evaluating the rates of recurrence and malignant transformation of LL lesions treated with CO laser and exploring relevant risk factors for recurrence or malignant transformation.

[Diagnosis and treatment of the fourth branchial fissure: a clinical report of 1 case and literature review].

The patient repeatedly suffer from pain in the left side neck for 4 years and had 1-2 recurrence per year. We used neck ultrasound and neck CT examination to find an abnormal soft tissue lumps exist in the patient's left neck root to the trachea esophageal ditch. Diagnostic analysis combines embryogenesis and anatomy, and the diagnosis results are infection with the fourth branchial fissure.

RUNX1 promotes MAPK signaling to increase tumor progression and metastasis via OPN in head and neck cancer.

Tumor progression and metastasis are still major burdens for head and neck squamous cell carcinoma (HNSCC). Runt-related transcription factor 1 (RUNX1) is involved in aggressive phenotypes in several cancers, while the molecular role of RUNX1 underlying cancer progression and metastasis of HNSCC remains largely unknown. In our study, RUNX1 expression was increased with disease progression in patients with HNSCC.

Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer.

Acquired resistance is a barrier to cetuximab efficacy in patients with head and neck squamous cell carcinoma (HNSCC). Secreted phosphoprotein 1 (SPP1) is involved in various biological processes, including immune responses, cancer progression, and prognosis in many cancers, while little is known in HNSCC. Bioinformatics methods were used to identify candidate genes and further in vivo and in vitro experiments were performed to examine and validate the function of SPP1.

Enumeration and molecular characterization of circulating tumor cell using an capture system in squamous cell carcinoma of head and neck.

Objective: Detection rate and isolation yield of circulating tumor cell (CTC) are low in squamous cell carcinoma of head and neck (SCCHN) with approaches due to limited sample volumes. In this study, we applied the CellCollector to capture CTC from peripheral blood.

Methods: In total, the study included 22 cases with 37 times of detection.

[Long-term efficacy of nasal endoscopic opticnerve decompression for traumatic optic neuropathy].

Objective: To analyze the long-term efficacy of nasal endoscopic opticnerve decompression for traumatic optic neuropathy(TON) and to explore its possible influencing factors.

Method: To summarize the clinical data of 39 cases underwent transnasal decompression, which were followed-up for more than 1 year. The data, including optic canal CT scanning, flashed-elicited visual-evoked potential (FVEP), preoperational vision and visual field examination were reviewed.

[Preliminary report on meticulous operation of thyroid lobectomy].

Objective: Thyroid lobectomy can be programmed to operate as "step by step". Each step must be performed meticulously with quality control, so as to minimize the complications of surgery.

Methods: From May 2013 to Auguest 2014, the meticulous thyroid operation was conducted in 72 cases (144 lobectomies).

[Preservation of parathyroid during the thyroidectomy].

Objective: To investigate the protection of the parathyroid in the total thyroidectomy to avoid the postoperative permanent hypoparathyroidism.

Methods: Forty-three consecutive cases underwent total thyroidectomy from June 2013 to June 2014 in Nanjing Tongren Hospital were reviewed. Of them 26 cases with malignant and 17 cases with benign thyroid diseases.

[The analysis of surgery effect of OSAHS children accompanied with sinusitis].

Objective: To discuss the clinical efficacy of adenoidectomy and tonsillectomy for the OSAHS children with sinusitis.

Method: Reviewing 112 cases of children with OSAHS, in which the 80 patients without chronic sinusitis, 32 ones with chronic sinusitis. Among them, 103 cases of children with adenoidectomy, tonsil resection, 9 cases adenoidectomy only.