Publications by authors named "Shana Zhou"
Article Synopsis
- Surface-enhanced Raman spectroscopy (SERS) is being utilized for diagnosing diseases by analyzing body fluids, particularly in understanding choledocholithiasis, a common digestive condition.
- This research evaluated bile samples from 46 patients to extract multi-component SERS spectral information, using techniques like Principal Component Analysis (PCA) to identify variations linked to different types of choledocholithiasis and their recurrence rates.
- By combining SERS with machine learning methods like Support Vector Machines (SVM), the study achieved high classification and prediction accuracy (99.2% for stone types and 95.2% for recurrence rates), highlighting the potential of this approach for enhancing disease diagnostics and understanding underlying mechanisms.
The adverse reactions caused by 6-thioguanine (6-TG) in anti-cancer treatment are closely related to the dose, leading to the urgent need for clinical monitoring of its concentration. In this work, a highly reproducible free-standing liquid membrane (FLM) surface-enhanced Raman spectroscopy (SERS) substrate was developed to detect 6-TG in human urine and serum quantitatively. Briefly, a prepared sample was adjusted to pH 2 and mixed with concentrated core-shell bimetallic nanoparticle (AgAu NP) suspension.
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