Clinical study on treatment of facial seborrheic dermatitis with intense pulsed light combined with 30% supramolecular salicylic acid.

Objectives: In this study, we investigated the effects of intense pulsed light (IPL) combined with 30% supramolecular salicylic acid on facial seborrheic dermatitis.

Methods: A total of 45 patients with mild or moderate facial seborrheic dermatitis were selected from our hospital between September 2018 and September 2019. The patients were divided into three groups consisting of 15 patients each.

Extensive Resistance of to Insecticides in Malaria-Endemic Areas of Hainan Province, China.

is one of the major malaria vectors and among the dominant species in Hainan Province, China. The resistance of to insecticides is an important threat to malaria control. However, few reports on insecticide resistance of were reported in this area.

A Cost-Effectiveness Analysis of Plasmodium falciparum Malaria Elimination in Hainan Province, 2002-2012.

In Hainan Province, China, great achievements in elimination of falciparum malaria have been made since 2010. There have been no locally acquired falciparum malaria cases since that time. The cost-effectiveness of elimination of falciparum malaria has been analyzed in Hainan Province.

Genetic diversity of Plasmodium vivax population before elimination of malaria in Hainan Province, China.

Background: Hainan Province is one of the most severe endemic regions with high transmission of Plasmodium falciparum and Plasmodium vivax in China. However, the incidence of P. falciparum and P.

Sensitivity of Plasmodium falciparum to antimalarial drugs in Hainan Island, China.

Pyronaridine and artesunate have been shown to be effective in falciparum malaria treatment. However, pyronaridine is rarely used in Hainan Island clinically, and artesunate is not widely used as a therapeutic agent. Instead, conventional antimalarial drugs, chloroquine and piperaquine, are used, explaining the emergence of chloroquine-resistant Plasmodium falciparum.

Lessons from malaria control to elimination: case study in Hainan and Yunnan provinces.

Reduction patterns of Plasmodium falciparum and P. vivax malaria transmission and the role of an integrated strategy of case management and vector control are compared between different ecological zones. The epidemiology of malaria in Hainan and Yunnan provinces was disparate, even though distinct malaria control strategies have been adapted to different situations based on risk group, vector behaviours, local health infrastructure, and environmental conditions.

Prevention measures and socio-economic development result in a decrease in malaria in Hainan, China.

Background: Historically, the incidence of malaria in the Hainan Province, China has been high. However, since 2001 the malaria incidence in Hainan has decreased due to large-scale, public educational, promotional campaigns and the adoption of preventative measures against malaria following the fast growth of socio-economic development. The present study analysed the correlation between prevention measures and social economic development on the incidence of malaria in Hainan from 2001 to 2013.

[Resistance of Anopheles sinensis to three common insecticides in Hainan Province].

Anopheles sinensis adults were collected by cow-baited trap in Haikou City, Sanya City, Lingshui County, Changjiang County and Qiongzhong County of Hainan Province during 2011-2013. The mosquitoes were exposed to insecticide impregnated papers with discriminating concentrations of DDT (4%), deltamethrin (0.05%), and malathion (5%) using WHO standard assays.

Eliminating Plasmodium falciparum in Hainan, China: a study on the use of behavioural change communication intervention to promote malaria prevention in mountain worker populations.

Background: In the island of Hainan, the great majority of malaria cases occur in mountain worker populations. Using the behavioral change communication (BCC) strategy, an interventional study was conducted to promote mountain worker malaria prevention at a test site. This study found the methods and measures that are suitable for malaria prevention among mountain worker populations.

[Analysis of malaria epidemic situation in Hainan Province, 2010].

A total of 78 malaria cases were reported in 2010 and the incidence of malaria in this year was 9 per million in Hainan Province. The positive rate of blood tests in floating population was higher than that in local residents, and the antibody-positive rate of residents was higher than that of students, and all the reported malaria patients received the correct treatment. The rate of the therapy for vivax malaria relapse was 96.

[Effect of comprehensive control on parasitic diseases in demonstration plot of Hainan Province].

Objective: To evaluate the effect of control on soil-transmitted nematode infections in the demonstration plot of integrated control on parasitic diseases, Hainan Province.

Methods: The plot (county) was divided into east, west, north, south and central areas and the villages in these areas were selected with the random sampling method, and then the residents in these villages were investigated with Kato-Katz technique for soil-transmitted nematode infections and with questionnaires for knowledge, attitude and practice (KAP) and so on before and after the implementation of the control measures. All the results were analyzed and compared statistically.

[Relationship between falciparum malaria incidence and the number of Anopheles dirus in Hainan from 2001 to 2008].

Objective: To analyze the relationship between falciparum malaria incidence and the number of Anopheles dirus in Hainan Province from 2001 to 2008, so as to provide the evidence for malaria control and prevention in Hainan Province.

Methods: The falciparum malaria incidence and the numbers of Anopheles dirus in 2001 - 2008 were calculated according to the data from Wuzhishan City and Qiongzhong County in Hainan Province. The Cochran-Armitage trend test was employed to explore the trend of falciparum malaria incidence.

[Resistance assay of malaria vectors to four kinds of common insecticides in some endemic areas of Hainan Province].

Objective: To determine the resistance of malaria vectors to four kinds of common insecticides in some endemic areas of Hainan Province.

Methods: Anopheline mosquitoes were collected between 2008 and 2010 from malaria endemic areas where insecticides were used for years. Anopheles dirus were collected from human-baited trap in Wangxia Town of Changjiang County.

[Epidemiology of soil-transmitted nematode infections in central mountain area of Hainan province].

The epidemiology of soil-transmitted intestinal nematodes were observed in the central mountain area without anti-helminthic therapy from 1986 to 2008. The results showed that the overall prevalence decreased from 96.4% in 1986 to 35.

Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests.

Background: Accurate diagnosis is essential for prompt and appropriate treatment of malaria. While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the sensitivity of RDTs has been reported to be highly variable. One possible factor contributing to variable test performance is the diversity of parasite antigens.

[Efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in Hainan, China].

Objective: To assess the therapeutic efficacy of the combinations dihydroartemisinin-piperaquine and artemether-lumefantrine in treating uncomplicated falciparum malaria cases in an area with high level resistance of Plasmodium falciparum to chloroquine in Hainan Province.

Methods: Patients aged 1 to 60 with uncomplicated P. falciparum infection and parasite density 1,000 to 200,000 parasites/microl were enrolled following an informed consent.

[Tribendimidine enteric coated tablet in treatment of 1,292 cases with intestinal nematode infection--a phase IV clinical trial].

Objective: To further evaluate the efficacy and safety of tribendimidine in treatment of adult patients with intestinal nematode infections.

Methods: An open and multi-center clinical trial was conducted in the provinces of Hainan, Sichuan and Guizhou. A total of 1,292 infected cases aged 15-70 years were enrolled in the study.

The control and surveillance of filariasis in Hainan Province, China.

Hainan is a single bancroftian filariasis endemic province where filariasis is prevalent in all 18 cities and counties. A program to control filariasis was started in 1953. The strategy of eliminating infection sources has been adopted as the principal intervention measure in filariasis control.

[Clinical observation on 899 children infected with intestinal nematodes and treated with tribendimidine enteric coated tablets].

Objective: To evaluate the efficacy and safety of tribendimidine in treatment of children with hookworm and Ascaris lumbricoides infections.

Methods: An open and multi-center clinical trial was conducted in the provinces of Hainan, Sichuan and Guizhou. 899 children aged 4-14 years were enrolled in the study.

[Study on the haplotypes of pfcrt polymorphism from Hainan Province].

Objective: To develop a method for comparing the haplotypes of pfcrt polymorphism of Hainan Province with those from other areas of the world.

Methods: Nested PCR was used to amplify the polymorphic region including codon 72 to 76 and 97 of pfcrt gene. The PCR products were digested by ApoI restriction endonuclease to determine the allelic types.

[Analysis on the relationship between malaria epidemics and NOAA-AVHRR NDVI in Hainan province].

Objective: To explore the relationship between malaria epidemics and NOAA-AVHRR NDVI.

Methods: Data on malaria were collected in all 19 counties in Hainan province from Feb, 1995 to Jan, 1996. Values regarding normalized difference vegetation index (NDVI)-related indicators including mean and maximum values of NDVI, the area proportion of NDVI values of 145- and 145+, months with NDVI values of 135+, 140+, 145+, 150+ of these counties in this period were all extracted from NOAA-AVHRR images, using ERDAS8.

[Study on the distribution of malaria in Hainan province through spatial local interpolation technique].

Objective: To explore the spatial distribution of malaria in Hainan province.

Methods: Maps of spatial distribution on malaria incidence in Hainan province from 1995 to 1999 were produced, using a spatial local interpolation technique in the ArcGIS 8.1 software.

[Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria].

Objective: To observe the therapeutic efficacy of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria.

Methods: Patients with Plasmodium falciparum were selected as the subjects, treated with a single dose of dihydroarteminisinin 160 mg combined with naphthoquine phosphate 400 mg (for adults) and followed up in preselective time by blood and temperature examination for 28 days after drug administration.

Results: 37 patients with falciparum malaria were treated and followed up.