Abnormal developmental of hippocampal subfields and amygdalar subnuclei volumes in young adults with heavy cannabis use: A three-year longitudinal study.

Background: Differences in the volumes of the hippocampus and amygdala have consistently been observed between young adults with heavy cannabis use relative to their non-using counterparts. However, it remains unclear whether the subfields of these functionally and structurally heterogenous regions exhibit similar patterns of change in young adults with long-term heavy cannabis use disorder (CUD).

Objectives: This study aims to investigate the effects of long-term heavy cannabis use in young adults on the subregional structures of the hippocampus and amygdala, as well as their longitudinal alterations.

Incidence, survival, and prognostic nomogram of patients with small intestinal neuroendocrine tumors: A SEER population-based study.

Small intestinal neuroendocrine tumors (SI-NETs) are a group of rare and significantly heterogeneous tumors with limited research currently available. This study aimed to investigate the incidence, survival, and prognostic factors of SI-NETs. We selected data from the surveillance, epidemiology, and end results (SEER) database between 2000 and 2019 and evaluated the incidence trend of SI-NETs during this period.

Association between systemic immunity-inflammation index and hypertension in US adults from NHANES 1999-2018.

Hypertension is a disease closely related to inflammation, and the systemic immunity-inflammation index (SII) is a new and easily detectable inflammatory marker. We aimed to investigate the association between SII and hypertension risk in a adult population in the US. We utilized data from the National Health and Nutrition Examination Survey spanning from 1999 to 2018, incorporating comprehensive information from adults reporting hypertension.

Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study.

Purpose: Limited attention was paid to focus on rectal melanomas (RM). This study aimed to evaluate the survival rate and prognostic factors of RM.

Methods: The data for patients with RM from Surveillance, Epidemiology, and End Results (SEER) database were used to analyze tumor survival.

Subcortical responses to music and speech are alike while cortical responses diverge.

Music and speech are encountered daily and are unique to human beings. Both are transformed by the auditory pathway from an initial acoustical encoding to higher level cognition. Studies of cortex have revealed distinct brain responses to music and speech, but differences may emerge in the cortex or may be inherited from different subcortical encoding.

Incidence, survival, and prognostic factors for patients with gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms: a SEER population-based study.

Background: Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) are a group of rare tumors with limited research currently available. This study aimed to analyze the incidence, survival, and prognostic factors of gastrointestinal MiNENs.

Methods: We included data from the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2019.

 sp. nov. (Annelida, Hesionidae) from southeastern China.

(Annelida, Hesionidae) is described based on specimens collected from the coast of southeast China. It is the first species described from the Indo-Pacific, although there are already nine valid species known from other parts of the world. This new species can be distinguished from the other species in having a palpostyle as long as the palpophore and double aciculae in both notopodia and neuropodia, and in bearing bifid furcate chaetae which have a smooth base on the shorter tine.

Incidence and survival of adenocarcinoma with mixed subtypes in patients with colorectal cancer.

Background: Limited attention was paid to adenocarcinoma with mixed subtypes (AM) of the colon and rectum due to its low incidence. This study aims to assess the frequency and survival rates of tumors in the population.

Methods: The data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2019.

Oncolytic vaccinia virus acts synergistically with anti-PD-L1 antibody to enhance the killing of colon cancer cells by CD8 T cells.

Both oncolytic vaccinia virus (OVV) and anti-PD-L1 antibody hold promise in cancer immunotherapy. Herein, we aimed to explore the possible synergistic effects of OVV and anti-PD-L1 on the growth and metastasis of colon cancer (CC) in mouse models. Microarray profiling of CC-related genes was first conducted.

The spatial variation and driving factors of soil total carbon and nitrogen in the Heihe River source region.

Soil carbon and nitrogen levels are key indicators of soil fertility and are used to assess ecological value and safeguard the environment. Previous studies have focused on the contributions of vegetation, topography, physical and chemical qualities, and meteorology to soil carbon and nitrogen change, but there has been little consideration of landscape and ecological environment types as potential driving forces. The study investigated the horizontal and vertical distribution and influencing factors of total carbon and total nitrogen in soil at 0-20 and 20-50 cm depths in the source region of the Heihe River.

Can EAT be an INOCA goalkeeper.

Ischemia with non-obstructive coronary artery (INOCA) is a blind spot of coronary artery disease (CAD). Such patients are often reassured but offered no specific care, that lead to a heightened risk of adverse cerebrovascular disease (CVD) outcomes. Epicardial adipose tissue (EAT) is proven to correlate independently with CAD and its severity, but it is unknown whether EAT is a specific and sensitive indicator of INOCA.

DSCA-Net: A depthwise separable convolutional neural network with attention mechanism for medical image segmentation.

Accurate segmentation is a basic and crucial step for medical image processing and analysis. In the last few years, U-Net, and its variants, have become widely adopted models in medical image segmentation tasks. However, the multiple training parameters of these models determines high computation complexity, which is impractical for further applications.

Organic photodiodes: device engineering and applications.

Organic photodiodes (OPDs) have shown great promise for potential applications in optical imaging, sensing, and communication due to their wide-range tunable photoelectrical properties, low-temperature facile processes, and excellent mechanical flexibility. Extensive research work has been carried out on exploring materials, device structures, physical mechanisms, and processing approaches to improve the performance of OPDs to the level of their inorganic counterparts. In addition, various system prototypes have been built based on the exhibited and attractive features of OPDs.

Speech-In-Noise Comprehension is Improved When Viewing a Deep-Neural-Network-Generated Talking Face.

Listening in a noisy environment is challenging, but many previous studies have demonstrated that comprehension of speech can be substantially improved by looking at the talker's face. We recently developed a deep neural network (DNN) based system that generates movies of a talking face from speech audio and a single face image. In this study, we aimed to quantify the benefits that such a system can bring to speech comprehension, especially in noise.

Efficacy and influencing factors of the four-step approach combining the situational simulation teaching method in the clinical practice of standardized training for residents.

Background And Aims: Clinical skills practice is an essential component in standardized residency training. However, traditionally skill training methods are dogmatic and not all residents are exposed to such prescribed situations during their residency. The aims of this study were to evaluate the effectiveness and influence factors of a four-step approach combining situational simulation teaching methods in clinical practice for residents.

Efficient Optoelectronic Devices Enabled by Near-Infrared Organic Semiconductors with a Photoresponse beyond 1050 nm.

Organic optoelectronic devices exhibit distinctive photoresponse to the near-infrared (NIR) light and show great potential in many fields. However, the optoelectronic properties of the existing devices hardly meet the technical requirements of new applications such as energy conversion and health sensing, thus raising the demand to develop high-performance NIR organic semiconductors. To address this issue, a new NIR material, namely, BFIC, is designed and synthesized by inserting fluorothieno[3,4-]thiophene (FTT) as a π-bridge.

Non-Fullerene Acceptors with an Optical Response over 1000 nm toward Efficient Organic Solar Cells.

Non-fullerene acceptors (NFAs) with near-infrared (NIR) absorption show promising advantages in organic solar cells (OSCs). However, only a few NFAs can extend the absorption spectra over 1000 nm, and their photovoltaic performance has been unsatisfactory so far. To address this issue, three new NFAs, namely, 6-IFIC, 6-IF2F, and 6-IF4F, were synthesized by simultaneously introducing π-bridge units and different end groups.

Protective effect and mechanisms of action of Mongolian medicine Sulongga-4 on pyloric ligation-induced gastroduodenal ulcer in rats.

Background: Sulongga-4 (SL-4) is a herbal formula used in traditional Mongolian medical clinics for the treatment of peptic ulcers and gastroenteritis, even though its pharmacological mechanism has not been well characterized.

Aim: To evaluate the protective effect and identify the mechanisms of action of SL-4 on gastroduodenal ulcer induced by pyloric ligation (PL) in rats.

Methods: PL was performed to induce gastric and duodenal ulcers in rats, which were then treated with oral SL-4 (1.

Gas-pressurized torrefaction of biomass wastes: Co-gasification of gas-pressurized torrefied biomass with coal.

Co-gasification of coal and biomass offers a relatively cleaner utilization way of fossil fuel. The fuel property improvement of biomass can not only improve the property of syngas but also enhance the synergistic effect during the co-gasification. In our previous work, a novel gas-pressurized (abbreviated as GP) torrefaction was proposed to effectively upgrade the biomass under mild condition.

Gas-pressurized torrefaction of biomass wastes: The optimization of pressurization condition and the pyrolysis of torrefied biomass.

A novel gas-pressurized (GP) torrefaction with high oxygen removal efficiency at mild temperature was proposed in our previous work. However, the optimal condition of the GP torrefaction and subsequent pyrolysis of the torrefied biomass were not clear. In this work, the effect of pressure on the GP torrefaction and pyrolysis product properties of the torrefied biomass were studied in detail.