High-altitude environments influence emotional biases. Nonetheless, the neural mechanisms underlying emotional facial processing, which could help explain depression due to high altitudes, remain unexplored. An emotional face recognition task was used to explore the impact of high-altitude hypoxia on emotional face recognition and event-related potentials were recorded in relation to a high-altitude group (n = 22) and a low-altitude group (n = 24).
View Article and Find Full Text PDFAs the third most important temperate fruit, Pear (Pyrus spp.) exhibits a remarkable genetic diversity and is classified into two mainly categories known as Asian pear and European pear. Although several pear genomes are available, most of the released versions are fragmented and not chromosome-level high-quality.
View Article and Find Full Text PDFObjective: This study aimed to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) concentrations and mortality in long-term prescription opioid users.
Methods: The study included 1856 long-term prescription opioid users from the National Health and Nutrition Examination Survey (NHANES, 2001-2018). Mortality status were determined by matching with the National Death Index (NDI) records until December 31, 2019.
As a country with abundant genetic resources of pigs, the domestication history of pigs in China and the adaptive evolution of Chinese pig breeds at different latitudes have rarely been elucidated at the genome-wide level. To fill this gap, we first assembled a high-quality chromosome-level genome of the Chenghua pig and used it as a benchmark to analyse the genomes of 272 samples from three genera of three continents. The divergence of the three species belonging to three genera, Phacochoerus africanus, Potamochoerus porcus, and Sus scrofa, was assessed.
View Article and Find Full Text PDFUltrasmall 4 to 6 nm nanoparticles of the metal-organic framework (MOF) UiO-66 (University of Oslo-66) were successfully prepared and embedded into the polymer Pebax 1657 to fabricate thin-film nanocomposite (TFN) membranes for CO/N and CO/CH separations. Furthermore, it has been demonstrated that ligand functionalization with amino (-NH) and nitro (-NO) groups significantly enhances the gas separation performance of the membranes. For CO/N separation, 7.
View Article and Find Full Text PDFSeparation of the C aromatic isomers, xylenes (PX, MX, and OX) and ethylbenzene (EB), is important to the petrochemical industry. Whereas physisorptive separation is an energy-efficient alternative to current processes, such as distillation, physisorbents do not generally exhibit strong C selectivity. Herein, we report the mixed-linker square lattice () coordination network [Zn(sba)(bis)]·DMF (, Hsba or = 4,4'-sulfonyldibenzoic acid, bis or = trans-4,4'-bis(1-imidazolyl)stilbene) and its C sorption properties.
View Article and Find Full Text PDFGlioma is one of the most common malignant tumors with characteristics of strong invasion and high postoperative recurrence rate, which seriously threatens human health. Nanoparticles as an emerging drug delivery system have promoted the development of glioma therapy. However, blocking of nanoparticles by the blood-brain barrier is still serious problem for the use of nanoparticles in glioma therapy.
View Article and Find Full Text PDFHistone acetyltransferase human males absent on the first (hMOF) is a member of MYST family which participates in posttranslational chromatin modification by controlling the acetylation level of histone H4K16. Abnormal activity of hMOF occurs in multiple cancers and biological alteration of hMOF expression can affect diverse cellular functions including cell proliferation, cell cycle progression and embryonic stem cells (ESCs) self-renewal. The relationship between hMOF and cisplatin resistance was investigated in The Cancer Genome Atlas (TCGA) and Genomics of Drug Sensitivity in Cancer (GDSC) database.
View Article and Find Full Text PDFTransdifferentiation of type II alveolar cells (AECII) is a major cause for radiation-induced lung fibrosis (RILF). Cell differentiation phenotype is determined by Lin28 (undifferentiated marker) and let-7 (differentiated marker) in a see-saw-pattern. Therefore, differentiation phenotype can be extrapolated based on Lin28/let-7 ratio.
View Article and Find Full Text PDFThe development of MOF-based efficient and reusable catalysts for hydrogen production under simulated sunlight irradiation, especially through overall water splitting, remains challenging. This is mainly due to either the inappropriate optical features or poor chemical stability of the given MOFs. Room temperature synthesis (RTS) of tetravalent MOFs is a promising strategy to design robust MOFs and their related (nano)composites.
View Article and Find Full Text PDFEncapsulating ultrasmall Cu nanoparticles inside Zr-MOFs to form core-shell architecture is very challenging but of interest for CO reduction. We report for the first time the incorporation of ultrasmall Cu NCs into a series of benchmark Zr-MOFs, without Cu NCs aggregation, via a scalable room temperature fabrication approach. The Cu NCs@MOFs core-shell composites show much enhanced reactivity in comparison to the Cu NCs confined in the pore of MOFs, regardless of their very similar intrinsic properties at the atomic level.
View Article and Find Full Text PDFObjective: To investigate current situation of facial wrinkles of male construction workers in Beijing area and to discuss the correlative factors.
Materials And Methods: A total of 149 male construction works and 63 male non-construction workers in Beijing were required to complete a questionnaire on their exposure to sunlight, dust, noise, and heat in their workplace environment. Their facial wrinkle scores were measured by VISIA Complexion Analysis System.
Background: Nematodes have evolved to survive in diverse ecological niches and can be a serious burden on agricultural economy, veterinary medicine, and public health. Antioxidant enzymes in parasitic nematodes play a critical role in defending against host oxidative stress. However, the features of the evolution of antioxidant enzymes in the phylum Nematoda remain elusive.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
February 2021
Room-temperature syntheses of metal-organic frameworks (MOFs) are of interest to meet the demand of the sustainable chemistry and are a pre-requisite for the incorporation of functional compounds in water-stable MOFs. However, only few routes under ambient conditions have been reported to produce metal(IV)-based MOFs. Reported here is a new versatile one-step synthesis of a series of highly porous M -oxocluster-based MOFs (M=Zr, Hf, Ce) at room temperature, including 8- or 12-connected micro/mesoporous solids with different functionalized organic ligands.
View Article and Find Full Text PDFBitter gourd () is a popular cultivated vegetable in Asian and African countries. To reveal the characteristics of the genomic structure, evolutionary trajectory, and genetic basis underlying the domestication of bitter gourd, we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries. The major gene clusters ( clusters) for the biosynthesis of cucurbitane triterpenoids, which confer a bitter taste, are highly conserved in cucumber, melon, and watermelon.
View Article and Find Full Text PDFAngiostrongylus cantonensis (rat lungworm) is the etiological agent of angiostrongyliasis, mainly causing eosinophilic meningitis or meningoencephalitis in human. Although the biology of A. cantonensis is relatively well known, little is understood about the mechanisms of the parasite's development and survival in definitive hosts, or its adaptation to a broad range of snail intermediate hosts.
View Article and Find Full Text PDFWheat is one of the most important staple crops worldwide and also an excellent model species for crop evolution and polyploidization studies. The breakthrough of sequencing the bread wheat genome and progenitor genomes lays the foundation to decipher the complexity of wheat origin and evolutionary process as well as the genetic consequences of polyploidization. In this study, we sequenced 3286 BACs from chromosome 7DL of bread wheat cv.
View Article and Find Full Text PDFTea is a globally consumed non-alcohol beverage with great economic importance. However, lack of the reference genome has largely hampered the utilization of precious tea plant genetic resources towards breeding. To address this issue, we previously generated a high-quality reference genome of tea plant using Illumina and PacBio sequencing technology, which produced a total of 2,124 Gb short and 125 Gb long read data, respectively.
View Article and Find Full Text PDFIn this study, we report a straightforward strategy for Hg ion detection. Fluorescent Au nanoparticles (NPs) were one-pot synthesized using a polymer (polyvinyl pyrrolidone [PVP]) as both capping and fluorescence agent. The as-synthesized PVP-Au NPs showed a remarkably rapid response selectively for Hg ions compared to 14 other metal ions.
View Article and Find Full Text PDFAutosomal recessive woolly hair/hypotrichosis (ARWH/HT: OMIM #278150/604379) is a rare hereditary hair disease characterized by tightly curled hair at birth which can lead to sparse hair later in life. The mutations in both LIPH and LPAR6/P2RY5 are responsible for autosomal recessive woolly hair with or without hypotrichosis (ARWH/HT). To conduct clinical and genetic investigations in four patients from three unrelated Chinese Han families with ARWH/HT, we performed mutation screening of LIPH and LPAR6/P2RY5 gene and identified four mutations in LIPH: c.
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