Aggregation and stability of nanoscale plastics in aquatic environment.

The widespread use and release of plastics in nature have raised global concerns about their impact on public health and the environment. While much research has been conducted on macro- and micro-sized plastics, the fate of nanoscale plastics remains unexplored. In this study, the aggregation kinetics and stability of polyethylene and polystyrene nanoscale plastics were investigated over a wide range of aquatic chemistries (pH, salt types (NaCl, CaCl MgCl), ionic strength) relevant to the natural environment.

Effects of Citrullus colocynthis L. in a rat model of diabetic neuropathy.

Objective: This study investigated the biochemical, histopathological and physiological effects of Citrullus colocynthis on peripheral neuropathy in rats with streptozotocin (STZ)-induced diabetes.

Methods: Seventy adult male Sprague-Dawley rats were included in the present study. Diabetes was induced in 60 rats, with a single intraperitoneal injection of STZ (65 mg/kg).

Uphill treadmill walking plus physical therapy versus physical therapy alone in the management of individuals with knee osteoarthritis: a randomized clinical trial.

Purpose: This study aims to compare the effectiveness of uphill walking and physical therapy versus physical therapy alone on knee pain, excursion ranges, stride length, and walking speed in individuals with knee osteoarthritis.

Methods: In this randomized clinical trial, 30 patients with knee osteoarthritis participated. Both control and intervention groups received 10-session physical therapy.

The Association Between Prolonged Proton Pump Inhibitors Use and Bone Mineral Density.

Background And Study Aim: Chronic use of proton-pump inhibitors (PPIs) has become a mainstay of therapy in common gastrointestinal diseases. A causal relationship between chronic PPI use and development of osteoporosis remains unproven. The aim of this study was to determine whether PPI users are more likely to develop alterations in bone density.

Relationship between wetting and capillary pressure in a crude oil/brine/rock system: From nano-scale to core-scale.

Hypothesis: The wetting behaviour is a key property of a porous medium that controls hydraulic conductivity in multiphase flow. While many porous materials, such as hydrocarbon reservoir rocks, are initially wetted by the aqueous phase, surface active components within the non-wetting phase can alter the wetting state of the solid. Close to the saturation endpoints wetting phase fluid films of nanometre thickness impact the wetting alteration process.

Effects of different non-Newtonian models on unsteady blood flow hemodynamics in patient-specific arterial models with in-vivo validation.

The aim of this study is to demonstrate the implications of using different blood rheological models in the simulation of blood flow dynamics in atherosclerotic coronary arteries. Computational fluid dynamics simulation was performed using three-dimensional (3D) patient-specific models of diseased left anterior descending (LAD) coronary arteries with varying degrees of stenosis severity. The three-dimensional arterial models were reconstructed from 3D quantitative coronary angiography, and input flow conditions were prescribed with blood flow conditions measured in-vivo.

Author Correction: Thymoquinone therapy remediates elevated brain tissue inflammatory mediators induced by chronic administration of food preservatives.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Efficient wound healing composite hydrogel using Egyptian Avena sativa L. polysaccharide containing β-glucan.

The purpose of this study was to develop an efficient wound healing PVA-biopolymer composite hydrogel using the polysaccharide derived from Egyptian Avena sativa L. The prepared polysaccharide showed high β-glucan content which accelerates wound healing. The β-glucan content was 13.

Zearalenone and ß-Zearalenol But Not Their Glucosides Inhibit Heat Shock Protein 90 ATPase Activity.

The mycotoxin zearalenone (ZEN) is produced by many plant pathogenic species. It is well known for its estrogenic activity in humans and animals, but whether ZEN has a role in plant-pathogen interaction and which process it is targeting was so far unclear. We found that treatment of seedlings with ZEN induced transcription of the gene.

Enhanced Kinetic Removal of Ciprofloxacin onto Metal-Organic Frameworks by Sonication, Process Optimization and Metal Leaching Study.

Metal-organic frameworks (MOFs) are currently recognized as unique platforms for environmental studies. This study evaluated the potential of nine MOFs from ZIF-8, ZIF-67, and UIO-66 families for the removal of ciprofloxacin (CIP), a toxic, bio-accumulative, and persistent fluoroquinolone antibiotic. ZIF-67-SO, with a rhombic crystalline morphology and 1375 m/g BET surface area, has the highest CIP adsorption efficiency among the studied MOFs.

Nitric oxide mitigates salt stress effects of pepper seedlings by altering nutrient uptake, enzyme activity and osmolyte accumulation.

This study was planned to evaluate the role of exogenous application of sodium nitroprusside (SNP), a NO donor, on the deleterious effect of salinity in L. seedlings. Different NO doses (0, 50, 100 and 150 µM SNP) were foliarly applied to pepper seedlings grown under the non-saline and saline conditions (50, 100 and 150 mM of NaCl).

Hemostasis critical values among Iranian clinical laboratories "National Survey of 157 Clinical Laboratories".

Background: Immediate reporting of critical values or test results significantly outside the normal range has a growing role in the management of patients, especially in life-threatening conditions. Due to the lack of international consensus, diverse approaches are used for determination of thresholds, reporting, documentation, and follow-up. In this study, we assessed how Iranian laboratories manage critical values for hemostasis.

Predictive factors for gangrene complication in acute calculous cholecystitis.

Backgrounds/aims: Gallbladder gangrene is a grave complication of acute calculous cholecystitis that is difficult to detect preoperatively. Ultrasound could show a gallbladder wall that is more thickened. In addition, other clinical measures were reported to be possible predictive factors.

Bioassay-guided fractionation and identification of antidiabetic compounds from the rind of Var. nana.

This study aimed to evaluate the antidiabetic potential of the rind of var. nana. Acute oral toxicity test revealed the safety profile of its ethanolic extract.

Data on efficient removal of acid orange 7 by zeolitic imidazolate framework-8.

A water stable and hybrid nonporous adsorbent, cubic zeolitic imidazolate framework-8 (ZIF-8), was synthesized for Acid orange 7 (AO7) removal from aqueous solutions in batch mode. Central composite design was utilized to explore the individual and interaction effects of pH, AO7 concentration, ZIF-8 dosage and contact time on dye adsorption. A second order polynomial equation (R = 0.

Quantitative determination of concordance in localizing epileptic focus by component-based EEG-fMRI.

Background And Objective: Accurate seizure onset zone (SOZ) localization is an essential step in pre-surgical assessment of patients with refractory focal epilepsy. Complex pathophysiology of epileptic cerebral structures, seizure types and frequencies have not been considered as influential features for accurate identification of SOZ using EEG-fMRI. There is a crucial need to quantitatively measure concordance between presumed SOZ and IED-related BOLD response in different brain regions to improve SOZ delineation.

Evaluation of phosphate removal from aqueous solution using metal organic framework; isotherm, kinetic and thermodynamic study.

Background: Phosphate (PO ) is the main etiological factor of eutrophication in surface waters. Metal organic frameworks (MOFs) are novel hybrid materials with amazing structural properties that make them a prominent material for adsorption.

Methods: Zeolitic imidazolate framework 67 (ZIF-67), a water stable member of MOFs, with a truncated rhombic dodecahedron crystalline structure was synthesized in aqueous environment at room temperature and then characterized using XRD and SEM.

Semi-automated standardisation of melanin bleaching procedures of heavily pigmented melanocytic lesions for immunohistochemical analysis on an automated platform.

: The diagnosis of heavily pigmented melanocytic lesions is problematic. This is often compounded by lack of visibility of nuclear detail of tumour cells due to physical masking by melanin pigment. Similarly, there can be colour merging of chromogenic final reaction products with melanin, making an evidence of antigenic localisation problematic.

A Comprehensive Overview of Coagulation Factor V and Congenital Factor V Deficiency.

Coagulation factor (F) V is a glycoprotein that plays an essential role in the formation of the prothrombinase complex, which is critical for progressing clot formation. FV deficiency is a rare bleeding disorder with an estimated incidence of one per 1 million in the general population. The disorder is manifested with a wide array of clinical bleeding events.

Metabolomics of Type 1 and Type 2 Diabetes.

Type 1 and type 2 diabetes mellitus (DM) are chronic diseases that affect nearly 425 million people worldwide, leading to poor health outcomes and high health care costs. High-throughput metabolomics screening can provide vital insight into the pathophysiological pathways of DM and help in managing its effects. The primary aim of this study was to contribute to the understanding and management of DM by providing reliable evidence of the relationships between metabolites and type 1 diabetes (T1D) and metabolites and type 2 diabetes (T2D).

Economic Burden of Adult Patients with Moderate to Severe Atopic Dermatitis Indicated for Systemic Treatment.

Given the introduction of new therapies targeting specific immune pathways for atopic dermatitis (AD), information on the economic burden of AD patients is needed. Direct costs (medication use and healthcare resource utilization) and costs of productivity loss were studied in 90 adult patients with AD indicated for systemic treatment. Costs were calculated for patients with controlled (Investigator Global Assessment (IGA) 0-2) and uncontrolled (IGA 3-5) disease at inclusion.

Thymoquinone therapy remediates elevated brain tissue inflammatory mediators induced by chronic administration of food preservatives.

Continuous exposure to preservatives such as nitrite salts has deleterious effects on different organs. Meanwhile, Nigella sativa oil can remediate such organ dysfunction. Here, we studied the effect of consumption of thymoquinone (TQ); the main component of Nigella sativa oil on the brain damage induced by sodium nitrite.

Chemical and microbial quality of bottled drinking water in Gonabad city, Iran: Effect of time and storage conditions on microbial quality of bottled waters.

Reports from bottled water (BW) industries show a rapidly increasing rate of global bottled water consumption. The present paper contains data on chemical and microbial quality of bottled waters marketed in Gonabad city, Iran. The data on the effect of time and storing conditions on microbial quality of bottled water also is reported.