Applicability of Dynamic Risk Stratification for Differentiated Thyroid Cancer (DTC) in a Resource Limited Setting.

Dynamic risk stratification (DRS) in DTC has been considered necessary to deliver correct follow-up (FU) treatment, avoiding overtreatment of low risk/intermediate risk patients as well as inadequate treatment of high risk patients. However, it's clinical applicability has been questioned in comparison with more conventional FU protocols. We aimed to know the predictive reliability of DRS in monitoring FU of DTC in a resource-constrained setting across various risk groups, especially when compared with clinical examination alone.

Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.

Objective: To determine the outcome of definitive concurrent chemoradiation with platinum for locally advanced sinonasal carcinomas.

Study Design: Retrospective cohort.

Methods: Twenty-three nonsurgically and definitively treated patients diagnosed between July 1998 and February 2009 were analyzed.

Understanding the Risk Factors and Long-Term Consequences of Cisplatin-Associated Acute Kidney Injury: An Observational Cohort Study.

Acute kidney injury (AKI) is a well-known complication of cisplatin-based chemotherapy; however, its impact on long-term patient survival is unclear. We sought to determine the incidence and risk factors for development of cisplatin-associated AKI and its impact on long-term renal function and patient survival. We identified 233 patients who received 629 cycles of high-dose cisplatin (99±9mg/m2) for treatment of head and neck cancer between 2005 and 2011.

Factors predictive of severity of osteoradionecrosis of the mandible.

Background: An analysis of risk factors predictive of severe mandibular osteoradionecrosis (ORN) is needed to aid prophylaxis and management of this condition.

Methods: We retrospectively analyzed 46 patients diagnosed between June 2002 and March 2009: 93% had mandibular ORN, which was staged 0 to III (Store and Boysen). Patient, tumor, treatment-related, and other variables were analyzed for association with mandibular ORN severity.

The role of distraction osteogenesis in mandibular reconstruction.

Purpose Of Review: Distraction osteogenesis is finding increasing application in the management of mandibular defects. It provides an alternative method of mandibular reconstruction in varied clinical settings, notably following trauma and ablation of malignant tumors. Many recent studies have explored modifications in surgical technique, refinements in device design, and experiments in animal models.

Role of socioeconomic factors in deep neck abscess: A prospective study of 120 patients.

Objective: To assess the socioeconomic factors, presentation, aetiological factors, microbiology, and management of deep neck abscesses.

Design: Prospective study.

Setting: Tertiary health care centre.

Pharyngeal perforation with deep neck abscess secondary to isolated hyoid bone fracture.

We report the case of a 26-year-old man who presented to us with dysphagia secondary to blunt trauma to the neck. The patient was found to have a hyoid bone fracture with pharyngeal perforation and resultant neck abscess. The patient responded to prompt surgical and medical management.