J Indian Soc Periodontol
May 2023
Fibrosarcoma is a rare malignancy of fibroblasts that seldom occurs in the oral cavity. Although rare, fibrosarcoma is an aggressive lesion associated with a poor survival rate. The occurrence of such a highly aggressive lesion on the gingiva is a diagnostic challenge for the clinician.
View Article and Find Full Text PDFCorona Virus Disease 2019 (COVID 2019), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a dreadful infectious disease which has emerged as one of the most significant medical emergency affecting everyone directly or indirectly. COVID 2019 is a multisystem disease and causes severe immunosuppression. Initially thought to affect mainly the respiratory system, it strikes all vital organ systems and cause defects in cardio-circulatory, respiratory system and gastrointestinal systems to name a few leading to copious biochemical alterations.
View Article and Find Full Text PDFAmeloblastoma, a benign but locally aggressive odontogenic tumor, often demonstrates metastasis despite benign histological features and this variant is termed as metastasizing ameloblastoma (METAM). It was classified under the malignant category in the 2005 WHO but has been re-classified under benign epithelial odontogenic tumors in the latest 2017 WHO classification. The present review aimed at gathering the available data on METAM to update the current cognizance about the pathology.
View Article and Find Full Text PDFContext: The malignant transformation potential of oral lichen planus (OLP) and related lesions is a subject of great controversy.
Aim: The aim of this study was to compare the expression of proteins related to apoptosis and tumour suppressor gene processes in OLP, oral lichenoid reaction (OLR) and oral lichenoid dysplasia (OLD).
Materials And Methods: The immunohistochemical study was carried out to investigate the expressions of survivin and p53 in a total of 30 lesional biopsy specimens - 10 cases each of OLP, OLR and OLD.
Context: With the ever-changing field of criminal justice, the constant revision of criteria for acceptable evidence by the judiciary poses new challenges in forensic investigation. The applicability of cheiloscopy in individual identification is an area of extensive research in recent years.
Objectives: The aim of the present study was to determine the distribution of different lip print patterns in North Kerala population, to assess any sexual dimorphism in lip patterns, and to correlate lip print patterns with ABO and Rh blood groups.
J Oral Maxillofac Pathol
January 2017
Background And Objectives: Globally, the prevalence of diabetes is soaring high in the recent times. There is an ardent search in the scientific community for a reliable and cheap early predictor which can serve the purpose of mass screening of a genetically vulnerable population. Hence, the present study was conducted to assess the predictive role of cheiloscopy on type II diabetes mellitus (T2DM).
View Article and Find Full Text PDFBackground: The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at a Tertiary Health Institution in Kerala and compare these data with those of previously reported studies.
Materials And Methods: The patient case files from the Department of Oral and Maxillofacial Pathology during the period between January 2007 and December 2011 were reviewed for cases of RHLs of the oral cavity. Both clinical and histopathological diagnoses of reactive lesions were selected for the study.
J Oral Maxillofac Pathol
November 2015
Numb chin syndrome (NCS), also known as mental nerve neuropathy, is characterized by facial and oral numbness restricted to the distribution of the mental nerve. Although not a common neuropathy, the clinical importance of this syndrome is its frequent association with malignancies. A 56-year-old Indian female reported with a complaint of numbness on the left side of chin.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
May 2014
Background: Oral submucous fibrosis (OSMF) is an insidious chronic fibrotic condition that involves the oral mucosa and occasionally the pharynx and esophagus. Vascularity in OSMF has always been a matter of debate. The prevailing concept is that epithelial atrophy occurs due to lack of perfusion but the recent data challenges this concept.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
September 2013
Plasma cell myeloma (PCM) is a clonal neoplastic proliferation of terminally differentiated B lymphocytes (plasma cells/myeloma cells) that involves the skeletal system in a multifocal fashion. Even though jaw involvement has been reported in as many as 30% of cases, myeloma cells infiltrating into the pulpal tissue is extremely rare. Here, we present a case of PCM in which myeloma cells are seen infiltrating into the pulpal tissue of 46.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
January 2013
Histoplasmosis is a systemic mycotic infection caused by the dimorphic fungus, Histoplasma capsulatum. Systemic histoplasmosis has emerged as an important opportunistic infection in human immunodeficiency virus (HIV) patients and those in endemic areas. Reported cases of histoplasmosis have been low in India with less than 50 cases being reported.
View Article and Find Full Text PDFLipomas are the most common form of benign mesenchymal tumors and are composed of mature adipocytes. They can occur anywhere in the body where fat is found and thus, called as the 'universal tumor' or the 'ubiquitous tumor'. Intraosseous lipomas (IOL) are among the rarest (0.
View Article and Find Full Text PDFAmelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
January 2012
Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion. Abundance of clear cells in an intraosseous mucoepidermoid carcinoma may complicate its histopathologic diagnosis. It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region.
View Article and Find Full Text PDFNecrotizing sialometaplasia, is a benign inflammatory lesion primarily involving the minor salivary glands of the hard palate. The lesion often presents itself as a deep-seated palatal ulcer with clinical and histological features similar to those of a malignant neoplasm. Here we report a case of necrotizing sialometaplasia in a 40-year-old female, present on the lateral border of the tongue, mimicking squamous cell carcinoma, clinically.
View Article and Find Full Text PDFSquamous cell carcinoma is the most common malignant neoplasm of the Oral Cavity, usually affecting individuals over 50 years of age. It rarely occurs in patients who are less than 40 years old (0.4-5.
View Article and Find Full Text PDFContext: No study highlighting the incidence of oral squamous cell carcinoma (OSCC) in young adults has been reported from North Kerala until now.
Aims: To study the cases of OSCC reported at our institution, with emphasis on the clinicopathologic variables in young adults.
Settings And Design: This was a retrospective study of OSCC cases reported from 2002 to 2007.
Med Oral Patol Oral Cir Bucal
October 2008
Objective: The purpose of the study was to evaluate the clinical presentation of pemphigus vulgaris in the oral cavity.
Study Design: A retrospective study of 71 cases of pemphigus vulgaris obtained over a period of 7 years from 1st January 2001 to 31st December 2007 in the Department of Oral Pathology, Government Dental College and Department of Dermatology, Government Medical College, Calicut was designed. Clinical details such as age, sex, intraoral distribution, extent of oral lesions, oral presentation, duration, oral involvement (whether primary or secondary) and mode of onset were noted from the files of corresponding Departments.
Objective: The purpose of the study was to analyze the frequency and distribution of gingival lesions in South Indian population.
Study Design: A retrospective study of 244 cases of gingival biopsies obtained over a period of 6 years from 1st January 2001 to 31st December 2006 in the Department of Oral Pathology, Government Dental College, Calicut was designed. The lesions were classified into neoplastic lesions and nonneoplastic lesions.
Sebaceous glands are common in the oral mucosa, but are not normally present with in the jaws. A case of an odontogenic keratocyst with sebaceous glands in the epithelium in a 12-year-old child is presented here, with special emphasis on its histogenesis.
View Article and Find Full Text PDFIntraosseous adenoid cystic carcinoma is an extremely rare neoplasm with only 17 cases reported previously. A case of primary intraosseous adenoid cystic carcinoma of the mandible with lung metastasis in a 45-year-old man is reported, together with a brief review of the literature.
View Article and Find Full Text PDFPemphigus vulgaris (PV) is a vesiculobullous lesion that produces intraepithelial blisters in skin and mucous membrane. The oral mucosa is often the first site to be affected by the disease. Although oral PVis a well characterized condition, the detailed clinical and histopathological study in Malabar population has not been reported.
View Article and Find Full Text PDFIndian J Pathol Microbiol
April 2007
Clear cell ameloblastoma is an odontogenic tumour with aggressive behaviour usually noticed in 6th decade of life. It is histologically characterized by an ameloblastomatous component intermixed with an extensive clear cell component. Here is a case report of an unusual occurrence in a 5-year-old child.
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