Low-Grade Adenosquamous Carcinoma of the Breast Developing Around a Localization Wire Fragment.

We present the case of a 67-year-old white woman with a history of benign biopsy results in the previous 10 years before she developed low-grade adenosquamous carcinoma around a residual localization wire fragment. A possible theory of carcinogenesis may be related to reparative epithelium in a healing biopsy site that underwent squamous metaplasia; alternately, there may have been carcinogenesis related to long-term metal exposure at the wire placement site. In vitro and in vivo studies have demonstrated a link between carcinogenesis and long-term exposure to various metals.

Breast arterial calcifications on mammograms do not predict coronary heart disease at coronary angiography.

Purpose: To examine, in women who underwent cardiac catheterization, whether breast arterial calcifications (BACs) seen at screening mammography correlate with coronary heart disease (CHD) seen at coronary angiography.

Materials And Methods: In an institutional review board-approved, HIPAA-compliant study, 172 women (mean age, 64.29 years +/- 11.

Pseudoangiomatous stromal hyperplasia of the breast: sonographic features with histopathologic correlation.

The objective of this study was to evaluate the spectrum of sonographic findings in pseudoangiomatous stromal hyperplasia (PASH) of the breast when it presents as a tumoral mass with pathologic correlation. Breast sonogram studies of 13 patients with 13 pathologically proven PASH lesions were retrospectively reviewed. The morphologic characteristics of the lesions as seen on ultrasound were evaluated and correlated with histopathologic findings.

Computer-aided classification of BI-RADS category 3 breast lesions.

Purpose: To evaluate a system for computer-aided classification (CAC) of lesions assigned to Breast Imaging Reporting and Data System (BI-RADS) category 3 at conventional mammographic interpretation.

Materials And Methods: A CAC system was used to analyze 106 cases of lesions (42 malignant) that at blinded retrospective interpretation were assigned to BI-RADS category 3 by at least two of four radiologists. The CAC system automatically extracted from the digitized mammograms quantitative features that characterized the lesions.

Can the size of microcalcifications predict malignancy of clusters at mammography?

Rationale And Objectives: The purpose of this study was to determine whether the size of mammographically detected microcalcifications is predictive of malignancy.

Materials And Methods: Two hundred sixty mammograms showing clustered microcalcifications with proven diagnoses (160 malignant, 100 benign) were respectively reviewed by experienced mammographers. Lesions that were obviously benign in appearance were excluded from the study.