Publications by authors named "Shalin Parekh"
Article Synopsis
- * Researchers found that while most children had normal neurodevelopmental scores, a significant number displayed issues, especially as they grew older; specific factors like low birth weight and maternal education influenced outcomes.
- * The findings suggest that children with sTOF may have elevated developmental concerns, and although the type of surgical intervention didn't seem to affect these outcomes, other risks like genetic syndromes are important to consider for early intervention.
To evaluate the association between initial management strategy of neonatal symptomatic Tetralogy of Fallot (sTOF) and later health-related quality of life (HRQOL) outcomes. We performed a multicenter, cross-sectional evaluation of a previously assembled cohort of infants with sTOF who underwent initial intervention at ≤ 30 days of age, between 2005 and 2017. Eligible patients' parents/guardians completed an age-appropriate Pediatric Quality of Life Inventory, a Pediatric Quality of Life Inventory Cardiac Module Heart Disease Symptoms Scale, and a parental survey.
View Article and Find Full Text PDFIntroduction: Sensory Processing Dysfunction (SPD) is common yet understudied, affecting up to one in six children with 40% experiencing co-occurring challenges with attention. The neural architecture of SPD with Attention Deficit and Hyperactivity Disorder (ADHD) (SPD+ADHD) versus SPD without ADHD (SPD-ADHD) has yet to be explored in diffusion tensor imaging (DTI) and Neurite Orientation Dispersion and Density Imaging (NODDI) has yet to be examined.
Methods: The present study computed DTI and NODDI biophysical model parameter maps of one hundred children with SPD.
Article Synopsis
- Diffusion tensor imaging (DTI) shows that there are differences in the brain's white matter between the left and right sides, but we don't fully understand why, especially in kids.
- Researchers think using a special type of imaging called Neurite Orientation Dispersion and Density Imaging (NODDI) can help explain these differences in children's brains with neurodevelopmental issues.
- The study involves 87 children, some with sensory over-responsivity (SOR) and some without, to see how their brain structures are different when looking at hemispheric lateralization.
Sensory Over-Responsivity (SOR) is an increasingly recognized challenge among children with neurodevelopmental concerns (NDC). To investigate, we characterized the incidence of auditory and tactile over-responsivity (AOR, TOR) among 82 children with NDC. We found that 70% of caregivers reported concern for their child's sensory reactions.
View Article and Find Full Text PDFPoor and asymmetric fetal growth have been associated with neonatal brain injury (BI) and worse neurodevelopmental outcomes (NDO) in the growth-restricted population due to placental insufficiency. We tested the hypothesis that postnatal markers of fetal growth (birthweight (BW), head circumference (HC), and head to body symmetry) are associated with preoperative white matter injury (WMI) and NDO in infants with single ventricle physiology (SVP) and d-transposition of great arteries (TGA). 173 term newborns (106 TGA; 67 SVP) at two sites had pre-operative brain MRI to assess for WMI and measures of microstructural brain development.
View Article and Find Full Text PDFBackground: Corrected age is typically applied when assessing the development of children born <32 weeks of gestation. There is no consensus as to whether corrected age should be applied when assessing children born late/moderately preterm (LMPT; 32-36 weeks of gestation).
Aims: This study explored the impact of corrected age on developmental test scores in infants born LMPT.
Accounting for deaths in neonatal trials: is there a correct approach?
Arch Dis Child Fetal Neonatal Ed
May 2015