Interplay Between TGF-β Signaling and MicroRNA in Diabetic Cardiomyopathy.

In diabetic patients, concomitant cardiovascular disease is the main factor contributing to their morbidity and mortality. Diabetic cardiomyopathy (DCM) is a form of cardiovascular disease associated with diabetes that can result in heart failure. Transforming growth factor-β (TGF-β) isoforms play a crucial role in heart remodeling and repair and are elevated and activated in myocardial disorders.

The impact of land price distortion on green development efficiency: mechanism discussion and empirical test.

Based on the panel data of 30 Chinese provinces, the Cobb-Douglas production function and GML index were constructed to measure the degree of land price distortion and green development efficiency, respectively, in China, and the System Generalised Method of Moments model was employed to explore the relationship between land price distortion and green development efficiency, and a mediating effect model was further constructed to analyse the transmission mechanism. The results show that, first, land price in China is characterised by a negative distortion, but the degree of negative distortion tends to decrease after 2010. Second, land price distortion significantly inhibits the improvement of green development efficiency; this conclusion still holds after a series of robustness tests, and land price distortion significantly promotes the progress of green technology, while significantly inhibiting the improvement of green technology efficiency.

Dimethyl 3,3'-[(4-nitro-phen-yl)methyl-ene]bis-(1-indole-2-carboxyl-ate) ethanol hemisolvate.

There are two main molecules in asymmetric unit of the title compound, CHNO·0.5CHOH. In both, the indole ring systems are approximately perpendicular to each other, at dihedral angles of 69.

Invasive Streptococcus pneumoniae infection among hospitalized patients in Jingzhou city, China, 2010-2012.

Background: Streptococcus pneumoniae (Sp) is a leading cause of bacterial pneumonia, meningitis, and sepsis and a major source of morbidity and mortality worldwide. Invasive pneumococcal disease (IPD) is defined as isolation of Sp from a normally sterile site, including blood or cerebrospinal fluid. The aim of this study is to describe outcomes as well as clinical and epidemiological characteristics of hospitalized IPD case patients in central China.

Clinical characteristics and factors associated with severe acute respiratory infection and influenza among children in Jingzhou, China.

Background: Influenza is an important cause of respiratory illness in children, but data are limited on hospitalized children with laboratory-confirmed influenza in China.

Methods: We conducted active surveillance for severe acute respiratory infection (SARI; fever and at least one sign or symptom of acute respiratory illness) among hospitalized pediatric patients in Jingzhou, Hubei Province, from April 2010 to April 2012. Data were collected from enrolled SARI patients on demographics, underlying health conditions, clinical course of illness, and outcomes.

Epidemiology, Seasonality and Treatment of Hospitalized Adults and Adolescents with Influenza in Jingzhou, China, 2010-2012.

Background: After the 2009 influenza A (H1N1) pandemic, we conducted hospital-based severe acute respiratory infection (SARI) surveillance in one central Chinese city to assess disease burden attributable to influenza among adults and adolescents.

Methods: We defined an adult SARI case as a hospitalized patient aged ≥ 15 years with temperature ≥38.0°C and at least one of the following: cough, sore throat, tachypnea, difficulty breathing, abnormal breath sounds on auscultation, sputum production, hemoptysis, chest pain, or chest radiograph consistent with pneumonia.

The substantial hospitalization burden of influenza in central China: surveillance for severe, acute respiratory infection, and influenza viruses, 2010-2012.

Background: Published data on influenza in severe acute respiratory infection (SARI) patients are limited. We conducted SARI surveillance in central China and estimated hospitalization rates of SARI attributable to influenza by viral type/subtype.

Methods: Surveillance was conducted at four hospitals in Jingzhou, China from 2010 to 2012.