Depression and anxiety symptoms are underestimated risk factors for postoperative prognosis in patients with Type 2 diabetes and peripheral artery disease undergoing partial foot amputation: Results from a prospective cohort study.

Objective: The aim of this study was to evaluate the prevalence and impact of depression and anxiety symptoms on post-operative prognosis and 1-year all-cause mortality in a large unique cohort of patients with Type 2 diabetes (T2D) and peripheral artery disease (PAD) after partial foot amputation (PFA).

Methods: Prospective cohort study with 1-year follow-up of 785 consecutive patients (mean age 60.9 ± 9.

Impact of Persistent Medication Adherence and Compliance with Lifestyle Recommendations on Major Cardiovascular Events and One-Year Mortality in Patients with Type 2 Diabetes and Advanced Stages of Atherosclerosis: Results From a Prospective Cohort Study.

Background: The aim of this study was to evaluate the impact of single and combined effects of persistent medication adherence and compliance with lifestyle recommendations on the incidence of major adverse cardiovascular events (MACE) and one-year all-cause mortality in patients with type 2 diabetes (T2D) and peripheral artery disease (PAD) after partial foot amputation (PFA), representing a unique cohort of patients with advanced stages of atherosclerosis.

Methods: This is a prospective cohort study of 785 consecutive patients (mean age 60.9 ± 9.

What is resistant arterial hypertension?

Purpose: The current review is to describe the definition and prevalence of resistant arterial hypertension (RAH), the difference between refractory hypertension, patient characteristics and major risk factors for RAH, how RAH is diagnosed, prognosis and outcomes for patients.

Materials And Methods: According to the WHO, approximately 1.28 billion adults aged 30-79 worldwide have arterial hypertension, and over 80% of them do not have blood pressure (BP) under control.

Renal denervation in the antihypertensive arsenal - knowns and known unknowns.

Even though it has been more than a decade since renal denervation (RDN) was first used to treat hypertension and an intense effort on researching this therapy has been made, it is still not clear how RDN fits into the antihypertensive arsenal. There is no question that RDN lowers blood pressure (BP), it does so to an extent at best corresponding to one antihypertensive drug. The procedure has an excellent safety record.

Structure and Magnetic Properties of a Nanosized Iron-Doped Bismuth Titanate Pyrochlore.

The nanosized (50-70 nm) pyrochlore BiFeTiO was prepared by a coprecipitation technique. Characterization of BiFeTiO was carried out by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), Raman spectroscopy, Mössbauer spectroscopy, and magnetic susceptibility measurements. The study of Fe doping in BiTiO was performed by means of density functional theory (DFT) calculations.

Opportunities and challenges of using social media big data to assess mental health consequences of the COVID-19 crisis and future major events.

The present commentary discusses how social media big data could be used in mental health research to assess the impact of major global crises such as the COVID-19 pandemic. We first provide a brief overview of the COVID-19 situation and the challenges associated with the assessment of its global impact on mental health using conventional methods. We then propose social media big data as a possible unconventional data source, provide illustrative examples of previous studies, and discuss the advantages and challenges associated with their use for mental health research.

Is Lone Hypertension a Risk Factor for More Severe COVID-19 Outcomes?

Background: Based on current evidence, it is not clear whether lone hypertension increases the risk for severe illness from COVID-19, or if increased risk is mainly associated with age, obesity and diabetes. The objective of the study was to evaluate whether lone hypertension is associated with increase mortality or a more severe course of COVID-19, and if treatment and control of hypertension mitigates this risk.

Methods: This is a prospective multi-center observational cohort study with 30-day outcomes of 9,531 consecutive SARS-CoV-2 PCR-positive patients ≥ 18 years old (41.

The new differential diagnostic test for the lichenoid drug eruption.

The differential diagnosis between lichenoid drug eruption (LDE) and lichen planus (LP) is difficult due to similar clinical and histological signs but important for treatment and prognosis. The purpose of this study was to propose the new diagnosis method for differentiate LDE from LP. During 2015-2018, 20 patients with confirmed LDE, 13 patients with LP and 134 controls were examined and treated at the Lenoblcenter.

Non-uniform electron conduction in weakly ordered SrFeMoO.

The electrical conductivity of SrFe1-xMoxO3-δ (0.07, 0.15, 0.

Tenfold risk increase of major cardiovascular events after high limb amputation with non-compliance for secondary prevention measures.

Background The aim of the study was to evaluate the impact of compliance with lifestyle recommendations and medication on 1-year prevention of major adverse cardiovascular events (MACE) in patients with type 2 diabetes (T2D) after trans-femoral amputation (TFA). Methods In this prospective single-center interventional cohort study, 179 consecutive T2D patients with symptomatic coronary artery disease (CAD) underwent 1-year follow-up examination after TFA in 2013. Lower limb and coronary artery CT angiography were provided before surgery; physical examination and laboratory tests were performed at baseline and every month after TFA for 1 year.

Coronary artery calcium score and coronary computed tomographic angiography for major perioperative cardiovascular complications in symptomatic diabetic patients undergoing trans-femoral amputation.

Objective: Perioperative risk for major cardiovascular events (MACE) is particularly high in patients with type 2 diabetes undergoing surgery for trans-femoral amputation (TFA). The aim of this study was to identify prognostic value of coronary calcium score (CACS) and coronary computed tomographic angiography (CCTA) for perioperative MACE in these patients.

Methods: In this prospective single center interventional cohort study, we evaluated 331 consecutive symptomatic patients with diabetes and without history of coronary intervention or myocardial infarction (MI) undergoing TFA in 2013.

[Emotional and Cognitive Disturbances in Addictions: interactions and correlations].

The literature data on the relationship between cognitive disorders and disorganized behavior influenced by affect in patients with addictions is reviewed. States of discomfort caused by withdrawal or pathological craving are discussed. A trend towards the development of integrative models based on the unity of cognitive and emotional processes is shown.