Vitamin C supplementation modulates crude oil contaminated water induced gravid uterine impaired contractile mechanism and foetal outcomes in Wistar rats.

Objectives: Crude oil is a common environmental contaminant that impacts the reproductive functions of women. Understanding the contractile mechanism of the gravid uterus and how it impacts fetal outcomes during crude oil-contaminated water (CCW) exposure is still evolving. This study investigates the effect of vitamin C supplementation during the ingestion of CCW from Bayelsa, Nigeria, on the contractile mechanism of the gravid uterus and fetal outcomes.

Preliminary Mechanistic Study on the Trachea Smooth Muscle Relaxant Activity of Aqueous Leaf Extract of in Male Wistar Rats.

Objectives: Aqueous leaf extract of (ALETP) has potent relaxant activity. However, this relaxant activity in respiratory smooth muscle remains uninvestigated. This study investigates the effect of ALETP on the contractile activity of tracheal smooth muscle (TSM) in adult male Wistar rats.

Effect of the beta-adrenergic blockade on intestinal lactate production and glycogen concentration in dogs infused with hexoses.

Objectives: To investigate effect of beta adrenergic blockade on intestinal lactate production and glycogen concentration in dogs infused with hexoses.

Methods: Experiments were carried out on 35 fasted male anaesthetized dogs weighing between 9 and 16 kg. The animals were divided into 7 (5 dogs per group) groups.

Uterine contractile activity and fetal outcome in rats treated with vitamin C during late gestational variable stress exposure.

Objectives: Stress responses vary throughout pregnancy and impact of late gestational variable stress (LGVS) with vitamin C supplementation on uterine contractility is barely explored. This study investigates fetal weight outcome and uterine contractile responses to pharmacological agents during LGVS exposure.

Methods: Twenty four nulliparous pregnant rats were divided into four groups of six.

Mechanisms of inhibitory activity of root extract of Carpolobia lutea G. Don on in vitro contractile responses of rabbit corpus carvernosum.

Introduction: Carpolobia lutea root extract (CLRE) has been reported to enhance penile erection. However, the mechanism involved is poorly understood. We investigated in vitro mechanisms of CLRE action on contractile activity of rabbit corpus cavernosum (CC).

Effects of aqueous leaf extract of Tridax procumbens on contractile activity of corpus cavernosum in N-nitro-l-arginine methyl ester-induced hypertensive male rats.

Objective: This study investigated the effects of aqueous leaf extract of Tridax procumbens (ALETP) on contractile activity of corpus cavernosum in N-nitro-l-arginine methyl ester (l-NAME)-induced hypertensive male rats.

Methods: Twenty normal, adult male rats (130-150 g) were divided into four groups of five rats each. Group I (control) was given normal saline (0.

Implication of caffeine consumption and recovery on the reproductive functions of adult male Wistar rats.

Background: This study assessed the impact of caffeine consumption and recovery on reproductive functions and fertility of Wistar rats.

Methods: Thirty-five adult male Wistar rats were divided into seven groups of five rats each. Group A (control) received distilled water (vehicle), while groups B, C, and D were treated orally with 10 mg/kg body weight (BW), 20 mg/kg BW, and 40 mg/kg BW caffeine, respectively, for 30 days.

Mechanism of vasorelaxation induced by Tridax procumbens extract in rat thoracic aorta.

Background/aim: Tridax procumbens (Linn) (Asteraceae) is one of the herbs widely distributed in many parts of the world. Its leaves have long been used for the treatment of hypertension in Nigeria. Previous studies have shown that aqueous leaves of T.

Comparative evaluation of the aphrodisiac efficacy of sildenafil and Carpolobia lutea root extract in male rabbits.

Aims: In spite of the folkloric use of the root of Carpolobia lutea as a sexual stimulant in man, there has been limited scientific proof of its efficacy. This study compares the efficacy of methanol extract of C. lutea root (MECLR) and sildenafil on the sexual activity of male rabbits.

Comprehensive assessment of the effect of root extract on male reproductive activity in albino rats.

To evaluate the effect of methanol extract from the root on male reproductive activity. Male albino rats were treated orally with distilled water (vehicle for the extract; control) and 50, 100 and 150 mg kg body weight of root extract for 8 weeks. Each group had its own recovery.