High demand of bioactive molecules (food additives, antibiotics, plant growth enhancers, cosmetics, pigments and other commercial products) is the prime need for the betterment of human life where the applicability of the synthetic chemical product is on the saturation due to associated toxicity and ornamentations. It has been noticed that the discovery and productivity of such molecules in natural scenarios are limited due to low cellular yields as well as less optimized conventional methods. In this respect, microbial cell factories timely fulfilling the requirement of synthesizing bioactive molecules by improving production yield and screening more promising structural homologues of the native molecule.
View Article and Find Full Text PDFLocal anesthetic (LA) agents are commonly employed during surgical procedures in dentistry to control pain. There are a variety of LA agents available in the market with different concentration of adrenaline added to increase the efficacy. The systemic effects of adrenaline used as vasoconstrictors in LA solution are short lived or transient in nature; however, there are instances of associated cardiovascular problems.
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