The significance of lower uterine segment involvement in endometrial cancer.

Background: Limited data suggests lower uterine segment involvement (LUSI) in endometrial cancer may be associated with other poor prognostic factors. We assessed the unclear impact of LUSI on prognosis in endometrial cancer.

Method: ology: A revision of pathological samples following surgical staging between the years 2002-2022 was performed and clinical data collected from patients' records.

Contribution of Solar Radiation and Pollution to Parkinson's Disease.

. Parkinson's disease (PD) is believed to develop from epigenetic modulation of gene expression through environmental factors that accounts for up to 85% of all PD cases. The main objective of this study was to examine the association between PD onset and a cumulative exposure to potentially modifiable ambient exposures.

Infantile hypertrophic pyloric stenosis: maternal diabetes and perinatal exposure to non-macrolide antibiotics.

Objective: Infant exposure to macrolide antibiotics is a risk factor for infantile hypertrophic pyloric stenosis (IHPS). The aim of the study was to establish whether perinatal exposure to non-macrolide antibiotics was a risk factor for IHPS.

Study Design: A retrospective matched case-control study was performed using a database including all children born at Soroka University Medical Centre between 2006 and 2018.

Ability to adapt to seasonal temperature extremes among atrial fibrillation patients. A nation-wide study of hospitalizations in Israel.

Background: In recent years, temperature fluctuations and adverse weather events have become major concerns, influencing overall mortality and morbidity. While the association between extreme temperatures and atrial fibrillation (AF) has been supported by research, there is limited evidence on the ability of AF patients to adapt to the changing temperatures. We explored this question among AF patients in Israel featured by extreme temperature conditions.

Cervical insufficiency a prologue for future pelvic organ prolapse?

Background: Preliminary evidence suggests that women with cervical oss insufficiency may have an increased risk to develop pelvic organ prolapse later in life, suggesting a common underlying collagen-oriented mechanism.

Objective: The objective of this study was to determine the association between cervical oss insufficiency and the subsequent development of pelvic organ prolapse.

Study Design: A matched, case-control study, including women who delivered at the Soroka University Medical Center.

Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.

Background: There is no clear-cut evidence in the existing medical literature of an association between iron deficiency and nonscarring alopecia.

Objective: The objective of the study was to conduct a systematic review of the medical literature on the prevalence of iron deficiency in women with nonscarring alopecia and compare their ferritin levels with those of women without this condition.

Methods: The electronic databases PubMed, Scopus, and Web of Science were searched between June 15, 2019, and July 24, 2019.

Lipid profile in mild subclinical hypothyroidism: systematic review and meta-analysis.

Introduction: Only severe subclinical hypothyroidism (SSCH) with TSH above 10 mIU/L is considered a risk factor of hyperlipidemia and cardiovascular disease. The results of published papers on mild subclinical hypothyroidism (MSCH) with TSH below10 mIU/L are contradictory. The objective of the study was to conduct a systematic review and meta-analysis on lipid profiles in a population of patients with MSCH (TSH10> mIU/L and normal T3, T4) in comparison with euthyroid subjects.

Health effects of desert dust storm events in the south-eastern Mediterranean: perceptions and practices of local stakeholders.

Background: The south-eastern Mediterranean experiences frequent desert dust storm events (DDS) that have been shown to be associated with adverse health effects.

Aims: This study assessed the perceptions and practices towards DDS of local authorities and stakeholders from 3 countries in the region, Cyprus, Greece and Israel.

Methods: Between October 2017 and April 2018, we administered a semi-structured questionnaire to regulatory authorities involved in public protection from DDS as well as social stakeholders in the 3 countries.

An impact of air pollution on moderate to severe relapses among multiple sclerosis patients.

Background: Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system with both a genetic and environmental component.

Objective: In the current study, we examined an association between incidence of MS moderate to severe relapses and exposure to air pollutants and meteorological exposures.

Methods: We enrolled MS patients in Southern Israel during 2000-2017.

Procedural training models among emergency medicine residency programs.

Objective: Optimal training methods remain controversial for rarely performed emergency procedures. Previous research has failed to demonstrate the superiority or inferiority of live anesthetized animal models (LAA) as compared to other modalities. Most of the data on LAA use comes from military contexts; less information is available for civilian emergency medicine (EM) training.

The long-term effect of short point of care ultrasound course on physicians' daily practice.

Background: The benefits of Point of Care Ultrasound (POCUS) are well established in the literature. As it is an operator-dependent modality, the operator is required to be skilled in obtaining and interpreting images. Physicians who are not trained in POCUS attend courses to acquire the basics in this field.

Cell-free DNA concentration in patients with clinical or mammographic suspicion of breast cancer.

Mammography has a crucial role in the detection of breast cancer (BC), yet it is not limitation-free. We hypothesized that the combination of mammography and cell-free DNA (cfDNA) levels may better discriminate patients with cancer. This prospective study included 259 participants suspected with BC before biopsy.

Accuracy of Focused Assessment with Sonography for Trauma (FAST) in Disaster Settings: A Meta-Analysis and Systematic Review.

Focused assessment with sonography for trauma (FAST) has been incorporated into the initial evaluation of trauma for decades. It is an important screening tool in the detection of intra-abdominal fluid. The objective of this study was to perform a systematic review of the use and accuracy of FAST as an imaging tool for blunt abdominal trauma in disaster/mass casualty settings.

Lung ultrasound compared to chest X-ray for diagnosis of pediatric pneumonia: A meta-analysis.

Objective: Although a clinical diagnosis, the standard initial imaging modality for patients with concern for pediatric community acquired pneumonia (pCAP) is a chest x-ray (CXR), which has a relatively high false negative rate, exposes patients to ionizing radiation, and may not be available in resource limited settings. The primary objective of this meta-analysis is to evaluate the accuracy of lung ultrasound (LUS) compared to CXR for the diagnosis of pCAP.

Methods: Data were collected via a systematic review of PubMed, EMBASE, and Web of Science with dates up to August 2017.