Publications by authors named "Shaista Ijaz Khan"
An innovative and universal imprinted sensor design for sandwich type detection of gemcitabine (GMT) in human serum samples is described. GMT is widely used in the treatment of different tumors, such as lung, ovarian, pancreatic, and breast cancer. The serum albumin-drug interaction was translated to design a multifunctional, ratiometric and dual mode silver nanoparticle based probe (BSA-Ag nanoprobe), as a read out system.
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- The need for effective chemosensors for CN ions arises from their harmful effects on human health and the environment.
- Two novel chemosensors, IF-1 and IF-2, were synthesized, with IF-2 demonstrating a strong selective binding to CN ions and a notable binding constant of 4.77 × 10 M and a low detection limit of 8.2 μM.
- The color change from colorless to yellow upon binding with CN ions, coupled with DFT studies revealing significant charge transfer, indicates that IF-2 is a promising candidate for creating test strips for CN ion detection.