Stability analysis of within-host SARS-CoV-2/HIV coinfection model.

The world has been suffering from the coronavirus disease 2019 (COVID-19) since late 2019. COVID-19 is caused by a virus called the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The human immunodeficiency virus (HIV) coinfection with SARS-CoV-2 has been reported in many patients around the world.

Stochastic Dynamics of the Latently Infected Cell Reservoir During HIV Infection.

The presence of cells latently infected with HIV is currently considered to be a major barrier to viral eradication within a patient. Here, we consider birth-death-immigration models for the latent cell population in a single patient, and present analytical results for the size of this population in the absence of treatment. We provide results both at steady state (viral set point), and during the non-equilibrium setting of early infection.