Podiatric physicians' perspectives on their role in promoting self-care in high-risk patients with diabetes.

Background: Foot self-care is key in preventing morbidity in high-risk diabetic patients. Motivational interviewing (MI) is an approach to encourage behavior change by patients that can be used in medical settings. The goal was to explore how podiatric physicians promote self-care in such patients and whether they use MI techniques.

Podiatrists' perspectives on their role in promoting self-care in high-risk patients with diabetes.

Abstract Self-foot care is key in preventing morbidity in high-risk diabetic patients. Motivational interviewing (MI) is an approach to encouraging behavioral change by patients that can be utilized in medical settings. Our goal was to explore how podiatrists promote self-care in such patients and if they use MI techniques.

Clinical review: The human experience with ghrelin administration.

Context: Ghrelin is an endogenous stimulator of GH and is implicated in a number of physiological processes. Clinical trials have been performed in a variety of patient populations, but there is no comprehensive review of the beneficial and adverse consequences of ghrelin administration to humans.

Evidence Acquisition: PubMed was utilized, and the reference list of each article was screened.

Motivational interviewing by podiatric physicians: a method for improving patient self-care of the diabetic foot.

Foot ulceration and lower-extremity amputation are devastating end-stage complications of diabetes. Despite agreement that diabetic foot self-care is a key factor in prevention of ulcers and amputation, there has only been limited success in influencing these behaviors among patients with diabetes. While most efforts have focused on increasing patient knowledge, knowledge and behavior are poorly correlated.

Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial.

Objective: To determine whether insulin sensitizers lower androgen levels and whether androgen suppression improves insulin resistance in nondiabetic postmenopausal women.

Design: Randomized, double-blind, placebo-controlled study.

Setting: Clinical and Translational Research Center of a university hospital.

Tyrosine kinase inhibitors and the thyroid as both an unintended and an intended target.

Objective: To review the association of the tyrosine kinase inhibitor sunitinib with hypothyroidism as well as the mean time to onset, possible mechanisms, reversibility, and mean duration.

Methods: We performed a MEDLINE search of the English-language literature using a combination of words ("sunitinib," "tyrosine kinase inhibitors," "thyroid," and "hypothyroidism") to identify original studies and reviews on sunitinib and thyroid function.

Results: Hypothyroidism was reported in 36% to 46% of patients who took sunitinib in prospective studies.