Publications by authors named "Shailesh V Mamdapure"
Curr Microbiol
October 2024
Article Synopsis
- Dental caries is a widespread, chronic oral infection caused by cariogenic bacteria, with drug resistance complicating treatment efforts.
- A study isolated and identified soil actinomycetes to test their antibacterial and anti-biofilm effects on antibiotic-resistant cariogenic bacteria, specifically Streptococcus mutans, an identified strong biofilm producer.
- The actinomycete isolate MMS-10 exhibited significant inhibitory effects on S. mutans growth and biofilm formation, and was identified as Streptomyces luridiscabiei, with its active compound being 2,4-Di-tert-butylphenol, showing potential as a drug-like agent.
