Publications by authors named "Shailendra Bhatnagar"
Article Synopsis
- A study was conducted to compare the accuracy of the stool-based CBNAAT test to the gastric aspirate CBNAAT test for diagnosing tuberculosis (TB) in children aged 0-18 years.
- It involved 100 children and found that the diagnostic accuracy was very similar: 81% for gastric aspirate and 80% for stool samples, with a high agreement rate of 97% between the two methods.
- The results suggest that stool CBNAAT is a reliable alternative to gastric aspirate CBNAAT for diagnosing TB in children, making the testing process easier and potentially more comfortable for young patients.
Comparison of Diagnostic Yield of Tuberculosis Loop-Mediated Isothermal Amplification Assay With Cartridge-Based Nucleic Acid Amplification Test, Acid-Fast Bacilli Microscopy, and Mycobacteria Growth Indicator Tube Culture in Children With Pulmonary Tuberculosis.
J Pediatric Infect Dis Soc
March 2021
Background: Cartridge-based nucleic acid amplification test (CB-NAAT) has been recommended for diagnosis of tuberculosis (TB) in children, but its wide use is limited by high cost and the need for well-equipped laboratories. This study was conducted in children with pulmonary TB to compare the diagnostic yield of TB-LAMP (loop-mediated isothermal amplification test) with CB-NAAT and other conventional methods.
Methods: Patients ≤ 14 years of age diagnosed with probable pulmonary TB were included in the study.