Publications by Shaikhutdinova E

Publications by authors named "Shaikhutdinova E"

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Characterization of Risk Factors for Modeling of Type 2 Diabetes Mellitus Induced by a High-Fat Diet in C57BL/6 Mice.

N A Borozdina E R Shaikhutdinova G A Slashcheva N A Goryacheva A V Zamyatina

Bull Exp Biol Med

February 2024

Type 2 diabetes mellitus develops due to a combination of genetic and environmental factors. C57BL/6 mice prone to obesity and leptin resistance were kept on a high-fat diet for 21 weeks. The animals showed a significant increase in fasting and postprandial glucose levels and body weight, the development of insulin resistance, and by week 18, an increase in the serum TNFα level.

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