Publications by authors named "Shahzaib Samad"

Background And Objective: Tricuspid valve replacement (TVR) is required when repair is not feasible, and it continues to be a relatively high-risk procedure owing to the complex medical and/or surgical profile of patients. The choice between mechanical and biological prostheses for TVR remains a subject of debate owing to their distinct advantages and disadvantages. This study aimed to analyse and compare the clinical outcomes of these two types of prostheses in the tricuspid position.

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Article Synopsis
  • Esophageal cancer is very rare in pregnant women, making up only 0.07%-0.1% of malignant tumors during pregnancy, and it progresses quickly, demanding prompt treatment.
  • A case study details a 30-year-old woman diagnosed with squamous cell carcinoma at 32 weeks of pregnancy after experiencing symptoms like hoarseness, dysphagia, and weight loss; the cancer metastasized to her parathyroid region and resulted in significant esophageal dilation.
  • After giving birth, the patient began a chemotherapy treatment plan; her follow-up imaging showed changes in her tumor, highlighting the necessity for vigilance in pregnant patients presenting with symptoms indicative of esophageal cancer.
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Cardiovascular illnesses (CVDs), particularly Coronary Artery Disease (CAD) and Ischemic Heart Disease (IHD), are major global health burdens, with a growing incidence in Pakistan. The development of PCSK9 inhibitors offers encouraging advantages in lowering LDL cholesterol and lowering cardiovascular risk, even though conservative treatments are still essential. However, access to them is severely hampered by their high cost, especially in environments with little resources.

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Background: The optimal treatment regimen for patients with Hughes syndrome remains unclear. Therefore, the authors sought to compare the outcomes of warfarin vs. factor Xa inhibitors in patients with Hughes syndrome.

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An article on the incidence of / mutations in Pakistan to those of ovarian, breast, and other cancers, as well as their newly found association to gastrointestinal cancers, and the incidence and mortality rates of these malignancies. It involves a perspective on the epidemiological significance of / mutations to various cancers and their immense risk to Pakistani families, as well as suggestions to tackle the problem, including possible advancement in their detection and treatment options to improve mortality rates.

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