Publications by authors named "Shahram Pour Bairanvand"
Iran Biomed J
January 2007
Article Synopsis
- Busulfan, a chemotherapy drug, negatively impacts sperm parameters and testis microstructure in mice, leading to decreased sperm counts and structural changes in the testes.
- Over a period of 8 weeks post-injection, significant decreases in sperm numbers and altered testicular structures were observed, although some changes appeared to reverse afterward.
- The study suggests that the adverse effects of busulfan are dose-dependent and primarily due to the inhibition of spermatogenesis, with potential for recovery after treatment.
