Cardiac response to hypertension treatment: an advanced echocardiographic evaluation.

Background: Hypertension is the most common reversible cause of cardiovascular disease worldwide and more than one billion individuals suffer from the disease. Constant heart exposure to increased afterload progresses to maladaptive remodeling, leading to cardiac dysfunction. In this study, we aimed to evaluate cardiac function in response to hypertension treatment.

Influence of Vitamin D Status on the Maintenance Dose of Warfarin in Patients Receiving Chronic Warfarin Therapy.

Introduction: Considering the anticoagulant actions of vitamin D, we hypothesize that vitamin D status might affect the required dose of warfarin for maintaining the therapeutic international normalized ratio (INR).

Methods: In a retrospective single-center cohort study, serum levels of 25-hydroxyvitamin D were assessed for 89 subjects receiving a stable dose of warfarin for 3 months or longer and had a stable INR between 2 and 3.5 for at least three consecutive visits.

Fibrinolytic Therapy in CCU Instead of Emergency Ward: How It Affects Door to Needle Time?

Background: The door-to-needle-time (DNT) is considered a standard time for scheduling thrombolysis for acute ST-segment elevation of myocardial infarction and this time can be reduced by minimizing the delay in starting thrombolytic treatment once the patient has reached to the hospital. This study was carried out on a sample of Iranian patients with acute myocardial infarction to determine the DNT in those after changing schedule of thrombolysis during 8 years from emergency to coronary care unit (CCU).

Methods: A descriptive cross-sectional study was carried out on all consecutive patients with a confirmed diagnosis of acute myocardial infarction admitted to the emergency ward of Ekbatan Hospital in Hamadan, Iran, within 2011 and had an indication of fibrinolytic therapy, which 47 patients were finally indicated to receive streptokinase in the part of CCU.

Evaluation of independent prognostic importance of hyperuricemia in hospital death after acute myocardial infarction.

Objective: To evaluate the role of hyperuricemia (serum uric acid level greater than 7 mg/dl) as an independent short term (in hospital) prognostic factor after acute myocardial infarction (AMI).

Methods: Included in the study were 2218 patients who were hospitalized with well established AMI from June 1996 through to December 2002 in the Coronary Care Unit of Ekbatan General Hospital, Hamedan University of Medical Sciences, Iran. All patients with exclusive criteria, were omitted from study.