Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression.

Brucellosis is a zoonotic caused by the which is a well-known infectious disease agent in domestic animals and if transmitted, it can cause infection in humans. Because brucellosis is contagious, its control depends on the eradication of the animal disease in farms. There are two vaccines based on the killed and/or weakened bacteria against and , but no recombinant vaccine is available for preventing the disease.

Role of miRNAs in mediating organophosphate compounds induced toxicity.

Organophosphate compounds (OPCs) are a diverse class of chemicals utilized in both industrial and agricultural settings. The exact molecular pathways that OPCs-induced toxicity is caused by are still being investigated, despite the fact that studies on this topic have been ongoing for a long time. As a result, it's important to identify innovative strategies to uncover these processes and further the understanding of the pathways involved in OPCs-induced toxicity.

Oxidative Stress Indices Changes in the Hearts of Rat Pups in Response to Maternal Buprenorphine Treatment during Gestation and Lactation.

This study aimed to assess the effects of Buprenorphine (BUP) on oxidative parameters in pups born to mothers exposed to the drug during gestation and lactation. Pregnant and lactating rats received BUP, 0.5 or 0.

The effects of L. and L. in metabolic syndrome patients: a systematic and meta-analysis study.

Introduction: This meta-analysis study assessed the effects of L. and L. in patients with metabolic syndrome.

Toxicity Evaluation of the Subacute Diazinon in Aged Male Rats: Hematological Aspects.

Background & Objective: Age-dependent Organophosphates (OPs) toxicity is a controversial topic. The present study was designed to investigate the effect of the sub-acute exposure to diazinon (DZN), one of the main OPs insecticides, on the hematological alterations in adult and aged male rats.

Methods: For the aim of this approach, the adult and aged rats were administered with DZN (15 mg/kg, orally) for 4 weeks.

Age-Related Diazinon Toxicity Impact on Blood Glucose, Lipid Profile and Selected Biochemical Indices in Male Rats.

Background: Diabetes and its complications are age-related diseases. Low-grade inflammation plays the main role in the aging processes. Diazinon (DZN), an organophosphate pesticide, has been found to induce metabolic disturbances.