Furthering Lifestyle Medicine Through the Donald A. Pegg Student Leadership Award: Reflections From 2023 Awardees.

The Donald A. Pegg Leadership Award, established in 2016 by the American College of Lifestyle Medicine (ACLM), recognizes emerging leaders in Lifestyle Medicine by awarding key seed funding to support Lifestyle Medicine Interest Groups (LMIGs) and conference support to attend the ACLM's annual conference. Through its generous support of students and LMIGs, the Pegg Award has been instrumental in catalyzing transformations in medical education, promoting awareness and integration of key Lifestyle Medicine principles into curricula.

Effect of continuity of team midwifery care on maternal and neonatal outcomes: a quasi-experimental study in Iran.

Midwife-led continuity of care models have been linked to better clinical outcomes in certain developed countries. However, there is a paucity of research on these models in developing nations. This quasi-experimental study was conducted on primiparous women who referred to one private midwifery center and two public hospitals in Ahvaz, Iran to evaluate the effect of team midwifery care on maternal and neonatal outcomes of pregnant women in Iran.

Ethical Climate in the Delivery Wards of Educational Hospitals in Southeast Iran.

Ethical climate is one of the important factors in the working climate of the hospital. Considering the difference in the Ethical climate in different departments of the hospital and the importance of the ethical climate in the delivery ward, this study aimed to assess the characteristics of hospital ethical climate in delivery ward of educational hospitals in southeast Iran. This descriptive and multi-center study was conducted from 2020 to 2021 in educational hospitals in southeast Iran.

A community resource to mass explore the wheat grain proteome and its application to the late-maturity alpha-amylase (LMA) problem.

Background: Late-maturity alpha-amylase (LMA) is a wheat genetic defect causing the synthesis of high isoelectric point alpha-amylase following a temperature shock during mid-grain development or prolonged cold throughout grain development, both leading to starch degradation. While the physiology is well understood, the biochemical mechanisms involved in grain LMA response remain unclear. We have applied high-throughput proteomics to 4,061 wheat flours displaying a range of LMA activities.

Enigma of Intramuscular Triamcinolone Acetonide (Kenalog) Efficacy.

Triamcinolone acetonide is a glucocorticosteroid used in standard clinical practice for its anti-inflammatory properties. Although it can be given via different routes of administration, the intramuscular route is unique compared with other corticosteroids-its effects remain potent over a longer period of time. We summarize the existing literature on the pharmacokinetic and pharmacodynamic mechanisms of intramuscular triamcinolone acetonide (Kenalog).

percutaneous penetration test overview.

Skin is a detailed, organized, and intricate niche in the human body. Topical and transdermal drugs are unique, in that their absorption is quite different from other routes of administration (oral, intramuscular, intravenous, etc.,.

The effect of evening primrose oil on cervical ripening and birth outcomes: A systematic review and meta-analysis.

Background And Purpose: The results of various studies on the effect of evening primrose oil (EPO) on cervical ripening are controversial. The purpose of this systematic review and meta-analysis was to assess the effect of EPO on cervical ripening and birth outcomes.

Materials And Methods: The Cochrane Library, Embase, PubMed, Scopus, Web of Science and Persian databases were searched for studies published from the inception of the databases up to February 2021 (search updated in May 2022).

Machine learning approaches for the prediction of lameness in dairy cows.

Lameness is one of the costliest health problems, as well as a welfare concern in dairy cows. However, it is difficult to detect cows with possible lameness, or the ones that are at risk of becoming lame e.g.

Integrated Decision Support Systems (IDSS) for Dairy Farming: A Discussion on How to Improve Their Sustained Adoption.

Dairy farm decision support systems (DSS) are tools which help dairy farmers to solve complex problems by improving the decision-making processes. In this paper, we are interested in newer generation, integrated DSS (IDSS), which additionally and concurrently: (1) receive continuous data feed from on-farm and off-farm data collection systems and (2) integrate more than one data stream to produce insightful outcomes. The scientific community and the allied dairy community have not been successful in developing, disseminating, and promoting a sustained adoption of IDSS.

Women's perception of continuity of team midwifery care in Iran: a qualitative content analysis.

Background: Understanding the pregnant women's perception of continuity of team midwifery care is necessary for introducing and implementing this model of midwife-led care in the Iranian maternity services. This qualitative study aims to explore women's perception of continuity of team midwifery care in Iran.

Methods: This research is a qualitative study conducted in Iran to explore women's perception of continuity of team midwifery care during pregnancy, birth and postpartum from October 2019 to August 2020.

International consensus definitions of clinical trial outcomes for kidney failure: 2020.

Kidney failure is an important outcome for patients, clinicians, researchers, healthcare systems, payers, and regulators. However, no harmonized international consensus definitions of kidney failure and key surrogates of progression to kidney failure exist specifically for clinical trials. The International Society of Nephrology convened an international multi-stakeholder meeting to develop consensus on this topic.

Is the quality of life different in single and remarried elderly?

Background: Due to increasing number of the world population, elderly individual's quality of life (QOL) is a matter of concern and marital status as one of the objective measures of QOL is of paramount importance. This study was done to compare the QOL between single and remarried elderly.

Materials And Methods: This case-control study was conducted on 200 elderly people in Qaen (Southern Khorasan province), Iran.

Use of Medicinal Plants and Synthetic Medicines by Pregnant Women in Kerman, Iran.

Background: Pregnant women take medicinal plants for various reasons, supposing that these plants are completely safe for their fetus and their own health. This study aims to identify all types of medicinal plants and synthetic medicines used by pregnant women in Kerman and to study factors related to their use.

Methods: In this cross-sectional study, 150 women who had received prenatal care at 12 health centers in Kerman in 2017 were interviewed.

Correction to: An open-label, single-dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of cinacalcet in pediatric subjects aged 28 days to < 6 years with chronic kidney disease receiving dialysis.

The original version of this article unfortunately contained three mistakes. In Table 1, the last line under "Key Inclusion Criteria" should read "Normal or clinically acceptable ECGs at screening and at day - 1." In addition, the abbreviation "IP" in the legend to Table 1 stands for "investigational product.

A randomized, double-blind, placebo-controlled study to assess the efficacy and safety of cinacalcet in pediatric patients with chronic kidney disease and secondary hyperparathyroidism receiving dialysis.

Background: This randomized phase 3 study evaluated the efficacy and safety of cinacalcet in children with secondary hyperparathyroidism (SHPT) receiving dialysis.

Methods: This study had double-blind and open-label phases. Eligible patients aged 6-< 18 years were randomized to cinacalcet (starting dose ≤ 0.

An open-label, single-dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of cinacalcet in pediatric subjects aged 28 days to < 6 years with chronic kidney disease receiving dialysis.

Background: Calcimimetics, shown to control biochemical parameters of secondary hyperparathyroidism (SHPT), have well-established safety and pharmacokinetic profiles in adult end-stage renal disease subjects treated with dialysis; however, such studies are limited in pediatric subjects.

Methods: In this study, the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cinacalcet were evaluated in children with chronic kidney disease (CKD) and SHPT receiving dialysis. Twelve subjects received a single dose of cinacalcet (0.

Optimization of reproductive management programs using lift chart analysis and cost-sensitive evaluation of classification errors.

The common practice on most commercial dairy farms is to inseminate all cows that are eligible for breeding, while ignoring (or absorbing) the costs associated with semen and labor directed toward low-fertility cows that are unlikely to conceive. Modern analytical methods, such as machine learning algorithms, can be applied to cow-specific explanatory variables for the purpose of computing probabilities of success or failure associated with upcoming insemination events. Lift chart analysis can identify subsets of high fertility cows that are likely to conceive and are therefore appropriate targets for insemination (e.

A randomized, open-label, dose-response study of losartan in hypertensive children.

Background And Objectives: Once-daily losartan reduces BP in a dose-dependent manner and is well tolerated in hypertensive children aged 6-16 years. This study assessed the dose-response relationship, safety, and tolerability of losartan in hypertensive children aged 6 months to 6 years.

Design, Setting, Participants, & Measurements: This was a 12-week, randomized, open-label, dose-ranging study, with a 2-year extension.

Short communication: Prediction of retention pay-off using a machine learning algorithm.

Replacement decisions have a major effect on dairy farm profitability. Dynamic programming (DP) has been widely studied to find the optimal replacement policies in dairy cattle. However, DP models are computationally intensive and might not be practical for daily decision making.

Prediction of insemination outcomes in Holstein dairy cattle using alternative machine learning algorithms.

When making the decision about whether or not to breed a given cow, knowledge about the expected outcome would have an economic impact on profitability of the breeding program and net income of the farm. The outcome of each breeding can be affected by many management and physiological features that vary between farms and interact with each other. Hence, the ability of machine learning algorithms to accommodate complex relationships in the data and missing values for explanatory variables makes these algorithms well suited for investigation of reproduction performance in dairy cattle.

Creatinine excretion rate and mortality in type 2 diabetes and nephropathy.

Objective: The creatinine excretion rate (CER) is inversely associated with mortality in the general and renal transplant population. The CER is a marker for muscle mass. It is unknown whether the CER is associated with outcome in diabetes.