Publications by authors named "Shahida Akhter"
Article Synopsis
- Heterozygous females with G6PD deficiency can experience serious health issues similar to hemizygous males and homozygous females, especially when exposed to oxidative stress from foods, drugs, or infections.
- Conventional enzyme assays typically detect G6PD deficiency in males and homozygous females, but may overlook heterozygous females due to a mix of normal and deficient red blood cells.
- This study demonstrated that high resolution melting (HRM) analysis is effective in identifying G6PD heterozygosity, finding more cases than the enzyme assay alone, which could help avert serious health risks for their newborns.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common X-linked human enzyme defect of red blood cells (RBCs). Individuals with this gene defect appear normal until exposed to oxidative stress which induces hemolysis. Consumption of certain foods such as fava beans, legumes; infection with bacteria or virus; and use of certain drugs such as primaquine, sulfa drugs etc.
View Article and Find Full Text PDFVariability study between Pap smear, Colposcopy and Cervical Histopathology findings.
J Pak Med Assoc
December 2015
Objective: To determine the agreement/variability between colposcopic findings, Pap smear cytology and histopathological diagnosis in gynaecology patients.
Methods: The cross-sectional cohort study was conducted from October 2010 to September 2011 at the Fauji Foundation Hospital, Rawalpindi, and comprised women who presented to the out-patient department with various gynaecological complaints. Colposcopy was performed in all women with unhealthy cervix during gynaecological examination, abnormal Pap smear report, recurrent vaginal discharge and postcoital bleeding.