Publications by authors named "Shahid Hussain Abro"

The present study investigated the status of peste des petits ruminants (PPR) for the first time in the camels of Pakistan. The samples were collected from the camel residing area of Sindh, Pakistan, and analyzed for breeds (Dhatti and Larri), districts (Tharparkar and Umerkot), age (young, adult, and old), and sexes (male and female). The sera samples (n = 200) were analyzed for the detection of antibodies using a competitive enzyme-linked immunosorbent assay (cELISA).

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Background: Infectious bronchitis virus (IBV) is a Gammacoronavirus of the family Coronaviridae and is a causative agent of an economically important disease in poultry. The spike glycoprotein of IBV is essential for host cell attachment, neutralization, and is involved in the induction of protective immunity. Previously obtained sequence data of the spike gene of IBV QX-like and Massachusetts strains were subjected to bioinformatics analysis.

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In recent years, strains of infectious bronchitis virus belonging to the QX-like genotype have been causing huge economic losses in commercial chicken flocks in different countries in Europe. In order to expand the knowledge of the molecular features of these viruses, we have sequenced and characterized the complete genome of European QX-like IBV strain CK/SWE/0658946/10, which was isolated in 2010 in Sweden. The genome is 27664 nucleotides in length, comprising six genes and 5' and 3' untranslated regions.

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Article Synopsis
  • Infectious bronchitis virus (IBV) is a major cause of economic losses in the poultry industry, with recent outbreaks in Sweden linked to poor broiler growth and low egg production.
  • Genetic analysis of recent IBV isolates shows a high similarity to QX-like strains and indicates a shift away from the older Massachusetts type, suggesting ongoing evolution of the virus.
  • Findings highlight the need for continuous monitoring and adaptation of vaccines and diagnostic methods to respond effectively to the changing dynamics of IBV infections.
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